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QUETIAPINE
SynDRA canonical compound SYN0001544 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · Rx/OTC |
| Primary target(s) | HTR2A |
| Mechanism of action | Serotonin receptor antagonist |
| Indication | bipolar disorder | schizophrenia |
| Disease area | neurology/psychiatry |
All known targets
- DRD2
- HTR2A
- HTR1D
- HTR1E
- HRH1
- HTR1A
- SLC6A2
- HTR1F
- HTR2C
- DRD1
- HTR1B
- HTR6
Mechanisms of action (all sources)
- Dopamine receptor antagonist
- Serotonin receptor antagonist
- HTR2A ANTAGONIST
- Serotonin 2a (5-HT2a) receptor antagonist
- HTR2C ANTAGONIST
- Serotonin 2c (5-HT2c) receptor antagonist
- DRD2 ANTAGONIST
- Dopamine D2 receptor antagonist
- HTR1A FULL AGONIST
- HTR1D FULL AGONIST
- HTR1E FULL AGONIST
- HTR1F FULL AGONIST
Drug classes
- Atypical Antipsychotic
- Antidepressive Agents
- Antipsychotic Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Psychotropic Drugs
- Tranquilizing Agents
ATC classes
Cross-references
Synonyms
- quetiapine fumarate
- quetiapine hemifumarate
- ICI 204,636
- seroquel
- Quetiapina
- Norsic
- Quetiapine extended release
- NSC-758918
- Atrolak xl
- Biquelle xl
- Brancico xl
- Ebesque xl
- Mintreleq xl
- Psyquet xl
- Seotiapim xl
- Seroquel
- Seroquel xl
- Sondate xl
- Tenprolide xl
- Zaluron xl
- Quetiapine [INN:BAN]
- UNII-BGL0JSY5SI
- BGL0JSY5SI
- CHEMBL716
- 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol
- CHEBI:8707
- C21H25N3O2S
- URKOMYMAXPYINW-UHFFFAOYSA-N
- 2-(2-(4-Dibenzo(b,f)(1,4)thiazepin-11-yl-1-piperazinyl)ethoxy)ethanol
- Ethanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-
- NCGC00095911-03
- Co-Quetiapine
- Quetiapinum
- Quetiapine hemifumarate
- Ketipinor (TN)
- Norsic (TN)
- Quetiapine (INN)
- Seroquel (Fumarate)
Reported adverse events
- GH
- Elderly
- Somnolence
- Irritability
- Vomiting
- Agranulocytosis
- Akathisia
- Constipation
- Depression
- Dyskinesia
- Dysphagia
- Hypotension
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