CARVEDILOL

SynDRA canonical compound SYN0001596 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · Rx/OTC
Primary target(s)	ADRB3
Mechanism of action	Adrenergic receptor antagonist
Indication	hypertension \| myocardial infarction \| myocardial infarction, hypertension
Disease area	cardiology

All known targets

ADRB1
ADRB2
ADRB3
ADRA1A
ADRA1D
RYR2
ADRA1B
KCNK2
HTR6
Htr1a
Htr1b
KCNH2

Mechanisms of action (all sources)

Adrenergic receptor antagonist
ADRB1 ANTAGONIST
Adrenergic receptor beta antagonist
ADRB2 ANTAGONIST
ADRB3 ANTAGONIST
ADRA1A ANTAGONIST
Adrenergic receptor alpha-1 antagonist
ADRA1D ANTAGONIST
ADRA1B ANTAGONIST
RYR2 INHIBITOR

Drug classes

Adrenergic alpha-Antagonists
Adrenergic beta1-Antagonists
Adrenergic beta2-Antagonists
alpha-Adrenergic Blocker
beta-Adrenergic Blocker
Adrenergic Agents
Adrenergic alpha-1 Receptor Antagonists
Adrenergic Antagonists
Adrenergic beta-Antagonists
Antihypertensive Agents
Antioxidants
Calcium Channel Blockers

ATC classes

C07A · BETA BLOCKING AGENTS
BETA BLOCKING AGENTS, OTHER COMBINATIONS

Cross-references

PubChem CID: 2585
ChEMBL: CHEMBL723
DrugBank: DB01136
ChEBI: CHEBI:3441
KEGG: D00255
RxNorm: 20352
Wikipedia: Carvedilol
TTD: D0W9LX
LINCS BRD: BRD-A10977446

Synonyms

Reported adverse events

Hypotension
Bradycardia
Hypertension
Urinary incontinence
Syncope
Tinnitus
Dizziness
Stevens-Johnson syndrome
Dry mouth
Hypokinesia
Insomnia
Nervousness

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