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FLUPHENAZINE
SynDRA canonical compound SYN0001598 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | DRD2 |
|---|
| Mechanism of action | Dopamine receptor antagonist |
|---|
| Indication | schizophrenia |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- DRD2
- DRD1
- HTR2A
- HTR7
- HTR6
- HRH1
- DRD5
- HTR1B
- HTR2B
- Htr7
- HTR1E
- HTR2C
Mechanisms of action (all sources)
- Dopamine receptor antagonist
- DRD2 ANTAGONIST
- Dopamine D2 receptor antagonist
- HTR2A ANTAGONIST
- HTR6 INVERSE AGONIST
- HTR7 INVERSE AGONIST
- DRD1 ANTAGONIST
- DRD5 ANTAGONIST
- HRH1 ANTAGONIST
- HTR1B MODULATOR
Drug classes
- Antipsychotic Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Dopamine Agents
- Dopamine Antagonists
- Neurotransmitter Agents
- Psychotropic Drugs
- Tranquilizing Agents
- Phenothiazine
ATC classes
Cross-references
Synonyms
- fluorfenazine
- fluorophenazine
- fluorphenazine
- ftorphenazine
- phthorphenazine
- fluphenazine hydrochloride
- fluphenazine dihydrochloride
- fluphenazine HCl
- flufenazin
- Flufenazina
- NSC-62323
- Triflumethazine
- Fluorophenazine
- Fluorphenazine
- Fluorfenazine
- Siqualon
- Elinol
- Phthorphenazine
- Vespazine
- Ftorphenazine
- Siqualine
- Sevinol
- Pacinol
- Fluphenazinum
- Prolixin
- Flufenazin
- Dapotum
- Flufenazina [DCIT]
- Yespazine
- SQ 4918
- Fluphenazine [INN:BAN]
- Moditen (Tabl or elixir)
- Fluphenazinum [INN-Latin]
- 2-(4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethanol
- 10-(3-(2-Hydroxyethyl)piperazinopropyl)-2-(trifluoromethyl)phenothiazine
- UNII-S79426A41Z
- HSDB 3334
- Prolixine
Reported adverse events
- Dyskinesia
- Hypotension
- Skin disorder
- Dystonia
- Hypertension
- Muscle rigidity
- Leukocytosis
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