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THIOGUANINE
SynDRA canonical compound SYN0001600 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | IMPDH2 |
|---|
| Mechanism of action | Purine antagonist |
|---|
| Indication | acute myeloid leukemia (AML) |
|---|
| Disease area | hematologic malignancy |
|---|
All known targets
- IMPDH1
- IMPDH2
- ABCC4
- ABCC5
- ADORA3
- ALOX15
- HPRT1
- MAPK3
- PTGS1
- REP
- XDH
- folK
Mechanisms of action (all sources)
- Purine antagonist
- IMPDH1 INHIBITOR
- Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor
- IMPDH2 INHIBITOR
Drug classes
- Antimetabolites
- Antimetabolites, Antineoplastic
- Antineoplastic Agents
- Noxae
ATC classes
Cross-references
Synonyms
- 6-Thioguanine
- tioguanine
- Tioguanine
- Tioguanina
- Thioguanine anhydrous
- Thioguanine hemihydrate
- Thioguanine, anhydrous
- Tioguanine hemihydrate
- NSC-752
- NSC-76504
- Lanvis
- Tabloid
- 6 Thioguanine
- THG
- ThioguaninGSK
- Tioguanin
- Tioguaninum
- Glaxo Wellcome Brand of Thioguanine
- Glaxo Wellcome Brand of Tioguanine
- GlaxoSmithKline Brand of Thioguanine
- GlaxoSmithKline Brand of Tioguanine
- Thioguanin-GSK
- Thioguanine Hemihydrate
- Thioguanine Monosodium Salt
- Thioguanine Tabloid
- Tioguanina Wellcome
- Tioguanine GlaxoSmithKline Brand
- Wellcome Brand of Thioguanine
- BW 5071
- DX4
- LT00455187
- Wellcome U3B
- Lanvis (TN)
- Thioguanine [USAN:BAN]
- Tioguanina[INN-Spanish]
- Tioguanine (INN)
- Tioguaninum [INN-Latin]
- Purine antimetabolite: antimetabolite: inhibits nucleic acid replication
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