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LOPINAVIR
SynDRA canonical compound SYN0001612 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | HIV protease inhibitor |
|---|
| Indication | human immunodeficiency virus (HIV-1) |
|---|
| Disease area | infectious disease |
|---|
All known targets
- ABCB1
- ABCG2
- HIV-1 protease
- KCNH2
- Zmpste24
- gag-pol
- pol
- protease
Mechanisms of action (all sources)
- protease inhibitor
- pol INHIBITOR
Drug classes
- HIV Protease Inhibitors
- Protease Inhibitor
- P-Glycoprotein Inhibitors
- Organic Anion Transporting Polypeptide 1B1 Inhibitors
- Cytochrome P450 3A Inhibitors
- Anti-HIV Agents
- Anti-Infective Agents
- Anti-Retroviral Agents
- Antiviral Agents
- Cytochrome P-450 CYP3A Inhibitors
- Cytochrome P-450 Enzyme Inhibitors
- Enzyme Inhibitors
ATC classes
Cross-references
Synonyms
- aluviran
- koletra
- Lopinavir-
- Aluviran
- Koletra
- Lopinavir, (s-(2s,4s,5s))-
- Lopinavirum
- A-157378-0
- A-157378.0
- ABT-378
- Lopinavir component of kaletra
- AIDS032937
- Aluvia (TN)
- Kaletra (TN)
- LPV
- Lopinavir (JAN/USAN/INN)
- Lopinavir [USAN:INN:BAN]
- RS-346
- A 157378
- ABT 157378
- ABT 378
- CHEBI:31781
- ABT378
- DTXCID6026456
- RefChem:5960
- ABT-378/r
- A157378.0
- J05AE06
- MFCD22628840
- NCGC00164576-02
- C37H48N4O5
- SMR002529581
- CAS-192725-17-0
- MFCD22373646
- Lopinavir?
- Lopinavir RS
- Lopinavir CRS
- UNII-2494G1JF75
Reported adverse events
- Pancreatitis
- Rash
- Amylase
- Dysgeusia
- Hepatotoxicity
- Bradyarrhythmia
- Toxic epidermal necrolysis
- Stevens-Johnson syndrome
- Abnormal dreams
- Headache
- Hypertension
- Myalgia
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