← SynDRA

RILUZOLE

SynDRA canonical compound SYN0001662 — structure-anchored drug synonym record

All known targets

• SCN5A
• SCN11A
• KCNN4
• SCN10A
• SCN9A
• SCN8A
• SCN7A
• SCN4A
• SCN3A
• SCN2A
• SCN1A
• TRPC5

Mechanisms of action (all sources)

• Glutamate inhibitor
• SCN1A BLOCKER
• Sodium channel alpha subunit blocker
• SCN5A BLOCKER
• SCN4A BLOCKER
• SCN7A BLOCKER
• SCN2A BLOCKER
• SCN9A BLOCKER
• SCN3A BLOCKER
• SCN11A BLOCKER
• SCN8A BLOCKER
• SCN10A BLOCKER

Drug classes

• Benzothiazole
• Anticonvulsants
• Central Nervous System Agents
• Excitatory Amino Acid Antagonists
• Neuroprotective Agents
• Neurotransmitter Agents
• Protective Agents

ATC classes

• N07X · OTHER NERVOUS SYSTEM DRUGS

Cross-references

• PubChem CID: 5070
• ChEMBL: CHEMBL744
• DrugBank: DB00740
• ChEBI: CHEBI:8863
• KEGG: D00775
• RxNorm: 35623
• PDB: 657
• Wikipedia: Riluzole
• TTD: D0H0KB
• LINCS BRD: BRD-K21283037

Synonyms

• rilutek
• rilutor
• 6-Trifluoromethoxybenzothiazol-2-ylamine
• riluzole hydrochloride
• riluzole HCl
• RP54274
• RP-54274
• Riluzol
• Tiglutik
• BHV-0223
• NSC-753433
• NSC-759823
• Exservan
• Rilutek
• Riluzole zentiva
• Teglutik
• Tiglutik kit
• Riluzolum
• Riluzole HCl
• ALBB-006046
• BF-37
• PK-26124
• R-116
• Rilutek (TN)
• Riluzol [INN-Spanish]
• Riluzole [USAN:INN]
• Riluzolum [INN-Latin]
• ZERO/001785
• Amino-2 trifluoromethoxy-6 benzothiazole
• Amino-2 trifluoromethoxy-6 benzothiazole [French]
• Riluzole (JAN/USAN/INN)
• PK-26124, RP-54274, Rilutek, Riluzole
• 2-Amino-6-(trifluoromethoxy)-benzothiazole
• 2-Amino-6-(trifluoromethoxy)benzothiazole
• 2-Amino-6-trifluoro-methoxybenzothiazole
• 2-amino-6-(trifluoromethoxy)-1,3-benzothiazole
• 2-amino-6-(trifluoromethoxy)benzo[d]thiazole
• 2-amino-6-(trifluoromethoxyl)benzothiazole

Reported adverse events

• Interstitial lung disease
• Nausea
• Pancreatitis
• Asthenia
• Neutropenia
• Tachycardia
• Abdominal pain
• Arthralgia
• Dizziness
• Dry mouth
• Eczema
• Flatulence