GLYCINE

SynDRA canonical compound SYN0001778 — structure-anchored drug synonym record

Clinical phase	Phase 1
Primary target(s)	AGXT \| AGXT2 \| ALAS1 \| ALAS2 \| BAAT \| GARS \| GATM \| GCAT \| GCSH \| GLDC \| GLRA1 \| GLRA2 \| GLRA3 \| GLRB \| GLYAT \| GLYATL1 \| GLYATL2 \| GNMT \| GPR18 \| GPRC6A \| GRIN1 \| GRIN2A \| GRIN2B \| GRIN2C \| GRIN2D \| GRIN3B \| GSS \| PIPOX \| SHMT1 \| SHMT2 \| SLC32A1 \| SLC36A1 \| SLC6A5 \| SLC6A9
Mechanism of action	glutamate receptor antagonist

All known targets

GRIN2A
GPRC6A
Grin2c
SLC6A9
SLC38A4
OR51E2
Grin3b
Grin3a
Grin2d
Grin2b
GRIN1
Grin2a

Mechanisms of action (all sources)

GRIN1 AGONIST
GRIN1 FULL AGONIST
GRIN2A AGONIST
GRIN2B AGONIST
GRIN2C AGONIST
GRIN2D AGONIST
GPRC6A FULL AGONIST
SLC38A4 MODULATOR
GRIN2A ANTAGONIST
TNNC1 STIMULATOR

Drug classes

Glycine Agents
Neurotransmitter Agents

ATC classes

B05C · IRRIGATING SOLUTIONS
A02A · ANTACIDS

Cross-references

PubChem CID: 750
ChEMBL: CHEMBL773
DrugBank: DB00145
ChEBI: CHEBI:15428
KEGG: D00011
RxNorm: 4919
PDB: GLY
Wikipedia: Glycine
TTD: D0M8AB

Synonyms

Reported adverse events

Electrolyte imbalance
Hypersensitivity
Infection
Pulmonary embolism
Refeeding syndrome
Alkalosis
Extravasation
Glycosuria
Local reaction
Metabolic acidosis
Death
Sepsis

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