← SynDRA
DEXMEDETOMIDINE
SynDRA canonical compound SYN0001797 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ADRA2A | ADRA2B | ADRA2C |
|---|
| Mechanism of action | adrenergic receptor agonist |
|---|
| Indication | sedative |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- ADRA2A
- ADRA2B
- ADRA2C
- ADRA1A
- ADRA1B
- ADRA1D
- Adra1a
- Adra1b
- Adra1d
- Adra2a
- Adra2b
- Adra2c
Mechanisms of action (all sources)
- ADRA2A AGONIST
- Adrenergic receptor alpha-2 agonist
- ADRA2C AGONIST
- ADRA2B AGONIST
- adrenergic receptor agonist
Drug classes
- Adrenergic alpha2-Agonists
- Central alpha-2 Adrenergic Agonist
- Adrenergic Agents
- Adrenergic Agonists
- Adrenergic alpha-2 Receptor Agonists
- Adrenergic alpha-Agonists
- Analgesics
- Analgesics, Non-Narcotic
- Central Nervous System Agents
- Central Nervous System Depressants
- Hypnotics and Sedatives
- Neurotransmitter Agents
ATC classes
- N05C · HYPNOTICS AND SEDATIVES
Cross-references
Synonyms
- (S)-Medetomidine
- dexmedetomidine hydrochloride
- dexdor
- dexmedetomidine HCl
- MPV1440
- precedex
- Dexmedetomidina
- Medetomidine, (s)-
- MPV-1440
- Dexmedetomidinum
- Precedex (TN)
- Dexmedetomidine (USAN/INN)
- (+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
- 4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
- 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
- CHEBI:4466
- 4-((1S)-1-(2,3-dimethylphenyl)ethyl)-1H-imidazole
- 4-((1S)-1-(2,3-dimethylphenyl)ethyl)-3H-imidazole
- 4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-3H-imidazole
- 1H-Imidazole, 4-(1-(2,3-dimethylphenyl)ethyl)-, (R)-
- RefChem:919964
- Hydrochloride, Dexmedetomidine
- DTXCID00820907
- N05CM18
- 1H-Imidazole, 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-
- (S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazole
- MFCD00880557
- (S)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
- 4-[(1~{S})-1-(2,3-dimethylphenyl)ethyl]-1~{H}-imidazole
- (S)-4-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole
- UNII-67VB76HONO
- Dexmedetomidinum [INN-Latin]
- Dexmedetomidina [INN-Spanish]
- Dexmedetomidine [USAN:INN:BAN]
- (+)-Medetomidine
- Dexdor (TN)
- 1H-Imidazole, 4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-
- Tocris-2023
Reported adverse events
- Bradycardia
- Hypotension
- Nausea
- Abdominal pain
- Acidosis
- Alanine aminotransferase increased
- Arrhythmia
- Blood pressure fluctuation
- Chills
- Hepatic function abnormal
- Hyperhidrosis
- Hypertension
Look up DEXMEDETOMIDINE in the interactive SynDRA portal →