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METHOTREXATE

SynDRA canonical compound SYN0001911 — structure-anchored drug synonym record

Clinical phaseLaunched
Approval statusApproved · Rx/OTC
Primary target(s)DHFR
Mechanism of actionDihydrofolate reductase inhibitor
Indicationacute lymphoblastic leukemia (ALL) | gestational choriocarcinoma | hydatidiform mole | psoriasis | rheumatoid arthritis
Disease areadermatology | hematologic malignancy | oncology | rheumatology

All known targets

Mechanisms of action (all sources)

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ATC classes

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Reported adverse events

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