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FASUDIL
SynDRA canonical compound SYN0001926 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | ROCK2 |
|---|
| Mechanism of action | Rho associated kinase inhibitor |
|---|
| Indication | cerebral vasospasm |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- ROCK1
- ROCK2
- PRKACA
- BMP2K
- PKN1
- RPS6KA5
- PRKD3
- PRKD2
- PRKCE
- PRKCD
- PKN3
- PKN2
Mechanisms of action (all sources)
- Rho associated kinase inhibitor
- ROCK2 INHIBITOR
- Rho-associated protein kinase inhibitor
- ROCK1 INHIBITOR
Drug classes
- Calcium Channel Blockers
- Calcium-Regulating Hormones and Agents
- Cardiovascular Agents
- Enzyme Inhibitors
- Membrane Transport Modulators
- Protein Kinase Inhibitors
- Vasodilator Agents
ATC classes
- C04A · PERIPHERAL VASODILATORS
Cross-references
Synonyms
- fasudil HCl semihydrate
- fasudil hydrochloride
- HA-1077
- fasudil hydrochloride hydrate
- HA1077
- fasudil HCl
- AT-877
- NSC-759827
- ZK-258594
- HA 1077
- Fasudil [INN]
- Fasudilum [INN-Latin]
- 1-(5-Isoquinolinesulfonyl)homopiperazine
- 1H-1,4-Diazepine, hexahydro-1-(5-isoquinolinylsulfonyl)-
- UNII-Q0CH43PGXS
- 5-(1,4-diazepane-1-sulfonyl)isoquinoline
- 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline
- (5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE
- AT877
- Q0CH43PGXS
- 5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE
- CHEMBL38380
- Hexahydro-1-(5-isoquinolinylsulfonyl)-1H-1,4-diazepine
- Fasudil (INN)
- Fasudilhydrochloride
- AT 877
- Fasudilum
- NSC 759827
- 5-[(Hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]isoquinoline
- CHEBI:43871
- 5-((HEXAHYDRO-1H-1,4-DIAZEPIN-1-YL)SULFONYL)ISOQUINOLINE
- RefChem:597170
- DTXCID9028201
- C04AX32
- HA-1077 (hydrochloride)
- MFCD00866182
- 5-((1,4-diazepan-1-yl)sulfonyl)isoquinoline
- Hexahydro-1-(5-isoquinolylsulfonyl)-1H-1,4-diazepine
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