← SynDRA

SERTRALINE

SynDRA canonical compound SYN0001969 — structure-anchored drug synonym record

All known targets

• SLC6A4
• SLC6A3
• CYP2C19
• ADRA1A
• KCNH2
• Tmem97
• Slc6a4
• Slc6a3
• Slc6a2
• Sigmar1
• SLC6A2
• SIGMAR1

Mechanisms of action (all sources)

• Serotonin receptor antagonist
• SLC6A4 INHIBITOR
• Serotonin transporter inhibitor
• selective serotonin reuptake inhibitor (SSRI)

Drug classes

• Serotonin Uptake Inhibitors
• Serotonin Reuptake Inhibitor
• Cytochrome P450 2D6 Inhibitors
• Antidepressive Agents
• Central Nervous System Agents
• Membrane Transport Modulators
• Neurotransmitter Agents
• Neurotransmitter Uptake Inhibitors
• Psychotropic Drugs
• Selective Serotonin Reuptake Inhibitors
• Serotonin Agents

ATC classes

• N06A · ANTIDEPRESSANTS

Cross-references

• PubChem CID: 68617
• ChEMBL: CHEMBL809
• DrugBank: DB01104
• ChEBI: CHEBI:9123
• KEGG: D00825
• RxNorm: 36437
• PDB: SRE
• Wikipedia: Sertraline
• TTD: D0K0TC
• LINCS BRD: BRD-K82036761

Synonyms

• sertraline hydrochloride
• sertraline HCl
• Sertralina
• Lustral
• SRE
• Sertralinum
• Sertralina [Spanish]
• Sertraline [Zoloft]
• Sertralinum [Latin]
• CP 51974
• Apo-Sertraline
• Lustral (TN)
• Sertraline (INN)
• Sertraline (Zoloft)
• Sertraline [INN:BAN]
• Zoloft (TN)
• (+)-Sertraline
• (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
• (1S-cis)-1,2,3,4-Tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine
• (1S-cis)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine
• QUC7NX6WMB
• cis-(+)-sertraline
• cp-51974
• (1S,4S)-sertraline
• CHEBI:9123
• Altruline
• Besitran
• Apo Sertraline
• Gen Sertraline
• Novo Sertraline
• ratio Sertraline
• Rhoxal sertraline
• RefChem:6215
• DTXCID203577
• N06AB06
• (R,R)-Sertraline
• C17H17Cl2N
• (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-tetralin-1-amine

Reported adverse events

• Suicide
• Dizziness
• Nausea
• Insomnia
• Agitation
• Constipation
• Dyspepsia
• Fatigue
• Somnolence
• Tremor
• Vomiting
• Ejaculation failure