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EFLORNITHINE

SynDRA canonical compound SYN0002086 — structure-anchored drug synonym record

All known targets

• ODC1
• ARG2
• Odc1

Mechanisms of action (all sources)

• Ornithine decarboxylase inhibitor
• ODC1 INHIBITOR

Drug classes

• Antiprotozoal
• Anti-Infective Agents
• Antineoplastic Agents
• Antiparasitic Agents
• Antiprotozoal Agents
• Enzyme Inhibitors
• Ornithine Decarboxylase Inhibitors
• Trypanocidal Agents
• Decarboxylase Inhibitors
• Decarboxylase Inhibitor

ATC classes

• D11A · OTHER DERMATOLOGICAL PREPARATIONS
• L01X · OTHER ANTINEOPLASTIC AGENTS
• P01C · AGENTS AGAINST LEISHMANIASIS AND TRYPANOSOMIASIS

Cross-references

• PubChem CID: 3009
• ChEMBL: CHEMBL830
• DrugBank: DB06243
• ChEBI: CHEBI:41948
• KEGG: D00829
• RxNorm: 569
• Wikipedia: Eflornithine
• TTD: D0X7JR
• LINCS BRD: BRD-A96292436

Synonyms

• eflornithine hydrochloride monohydrate
• eflornithine hydrochloride anhydrous
• vaniqa
• eflornithine hydrochloride
• elfornithine
• ornidyl
• alpha-(Difluoromethyl)-DL-ornithine
• eflornithine hydrochloride hydrate
• eflornithine HCl
• Eflornitina
• Ornidyl
• 2-(Difluoromethyl)ornithine
• alpha-Difluoromethylornithine
• Difluromethylornithine
• Eflornitina [Spanish]
• Eflornithinum [Latin]
• 2,5-diamino-2-(difluoromethyl)pentanoic acid
• N-Difluoromethylornithine
• DFMO (growth regulator)
• Eflornithine [INN:BAN]
• 2-(Difluoromethyl)-DL-ornithine
• DL-alpha-(Difluoromethyl)ornithine
• MDL 71782
• CCRIS 3295
• Ornithine, 2-(difluoromethyl)-
• Eflornithinum
• DFMO hydrochloride
• DFMO hydrochloride hydrate
• EFLORNITHINE HYDROCHLORIDE
• BMS 203522
• Alpha-DFMO HCl
• Alpha-Difluoromethylornithine hydrochloride
• CPP-1X
• Eflornithine (INN)
• Ornidyl (TN)
• DL-alpha-Difluoromethylornithine
• DL-alpha-Difluoromethylornithine hydrochloride hydrate
• D,L-alpha-Difluoromethylornithine

Reported adverse events

• Pseudofolliculitis
• Acne
• Alopecia
• Asthenia
• Dizziness
• Dyspepsia
• Erythema
• Folliculitis
• Headache
• Nausea
• Pruritus
• Rash