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LOXAPINE
SynDRA canonical compound SYN0002093 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | HTR6 |
|---|
| Mechanism of action | Serotonin receptor antagonist |
|---|
| Indication | schizophrenia |
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| Disease area | neurology/psychiatry |
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All known targets
- DRD2
- DRD4
- DRD3
- HTR2C
- HTR2A
- HTR6
- HRH1
- DRD1
- ADRA1A
- HTR1A
- HRH4
- HTR1E
Mechanisms of action (all sources)
- Dopamine receptor antagonist
- Serotonin receptor antagonist
- HTR2A ANTAGONIST
- Serotonin 2a (5-HT2a) receptor antagonist
- HTR2C ANTAGONIST
- Serotonin 2c (5-HT2c) receptor antagonist
- DRD2 ANTAGONIST
- D2-like dopamine receptor antagonist
- DRD3 ANTAGONIST
- DRD4 ANTAGONIST
- HTR2A INVERSE AGONIST
- HTR2C INVERSE AGONIST
Drug classes
- Antipsychotic Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Dopamine Agents
- Dopamine Antagonists
- Neurotransmitter Agents
- Psychotropic Drugs
- Tranquilizing Agents
ATC classes
Cross-references
Synonyms
- loxapin
- oxilapine
- loxapine succinate
- cloxazepine
- loxitane
- adasuve
- loxapine hydrochloride
- loxapine HCl
- loxipine maleate
- Loxapina
- CL 62,362
- CL-62362
- SUM-3170
- Adasuve
- Cloxazepine
- Dibenzacepin
- Dibenzoazepine
- Lossapina
- Loxapin
- Loxapinsuccinate
- Loxapinum
- Loxepine
- Oxilapine
- Lossapina [DCIT]
- Loxitane IM
- HF 3170
- HF3170
- Hydrofluoride 3170
- LW 3170
- S 805
- SUM 3170
- Loxapac (TN)
- Loxapina [INN-Spanish]
- Loxapinum [INN-Latin]
- Loxitane (TN)
- S-805;SUM-3170
- CL-71,563
- Loxapine (USAN/INN)
Reported adverse events
- Neuroleptic malignant syndrome
- Akathisia
- Dermatitis
- Dizziness
- Dry mouth
- Dyskinesia
- Dystonia
- Hepatocellular injury
- Nausea
- Tachycardia
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