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POMALIDOMIDE

SynDRA canonical compound SYN0002173 — structure-anchored drug synonym record

All known targets

• CRBN
• TNF
• CUL4A
• CYP2C19
• DDB1
• RBX1

Mechanisms of action (all sources)

• angiogenesis inhibitor
• Tumor necrosis factor production inhibitor
• CRBN INHIBITOR
• CRL4(CRBN) E3 ubiquitin ligase inhibitor
• DDB1 INHIBITOR
• CUL4A INHIBITOR
• RBX1 INHIBITOR
• CRBN BINDER
• CRBN MODULATOR

Drug classes

• Angiogenesis Inhibitors
• Antineoplastic Agents
• Growth Inhibitors
• Growth Substances
• Immunologic Factors
• Thalidomide Analog

ATC classes

• L04A · IMMUNOSUPPRESSANTS

Cross-references

• PubChem CID: 134780
• ChEMBL: CHEMBL43452
• DrugBank: DB08910
• ChEBI: CHEBI:72690
• KEGG: D08976
• RxNorm: 1369713
• Wikipedia: Pomalidomide
• TTD: D0A3ZU
• LINCS BRD: BRD-A12994259

Synonyms

• pomalyst
• actimid
• Pomalidomida
• Actimid
• CC-4047
• IMID-3
• IMID3
• Imnovid
• Imnovid (previously pomalidomide celgene)
• Pomalidomide accord
• Pomalidomide krka
• Pomalidomide viatris
• Pomalidomide zentiva
• Pomalyst
• Actimid (TN)
• Pomalidomide (Immunomodulator)
• 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
• CC 4047
• 4-Aminothalidomide
• 4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione
• 3-Amino-N-(2,6-dioxo-3-piperidyl)phthalimide
• 1H-Isoindole-1,3(2H)-dione, 4-amino-2-(2,6-dioxo-3-piperidinyl)-
• 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
• (S)-pomalidomide
• D2UX06XLB5
• CHEBI:72690
• MFCD12756407
• 4-amino-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
• 1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline
• 4-amino-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione
• 4-amino-2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione
• Pomalidomide (CC-4047)
• Pomalidomide [USAN:INN]
• UNII-D2UX06XLB5
• HSDB 8222
• Pomalyst (TN)
• CC4047
• Pomalidomide- Bio-X

Reported adverse events

• DVT
• Back pain
• Bone pain
• Cough
• Dizziness
• Febrile neutropenia
• Infection
• Nausea
• Neutropenia
• Pneumonia
• Pyrexia
• Thrombocytopenia