← SynDRA

LENALIDOMIDE

SynDRA canonical compound SYN0002185 — structure-anchored drug synonym record

All known targets

• CRBN
• TNF
• BRD4
• CUL4A
• DDB1
• RBX1

Mechanisms of action (all sources)

• Anti-cancer agent
• CRBN INHIBITOR
• CRL4(CRBN) E3 ubiquitin ligase inhibitor
• DDB1 INHIBITOR
• CUL4A INHIBITOR
• RBX1 INHIBITOR
• CRBN MODULATOR
• CRL4(CRBN) E3 ubiquitin ligase modulator
• DDB1 MODULATOR
• CUL4A MODULATOR
• RBX1 MODULATOR
• CRBN BINDER

Drug classes

• Angiogenesis Inhibitors
• Antineoplastic Agents
• Growth Inhibitors
• Growth Substances
• Immunologic Factors
• Thalidomide Analog

ATC classes

• L04A · IMMUNOSUPPRESSANTS

Cross-references

• PubChem CID: 216326
• ChEMBL: CHEMBL848
• DrugBank: DB00480
• ChEBI: CHEBI:63791
• KEGG: D04687
• RxNorm: 342369
• Wikipedia: Lenalidomide
• TTD: D0Q5NX
• LINCS BRD: BRD-A17883755

Synonyms

• lenalidomide hydrate
• revimid
• revlimid
• Lenalidomida
• CC-5013
• CDC-501
• NSC-747972
• SYP-1512
• Lenalidomide accord
• Lenalidomide mylan
• Revlimid
• Revamid
• Revimid
• Celgene brand of lenalidomide
• Lenalidomide [USAN]
• CC5013
• IMiD3
• IMiD3cpd
• ALBB-015321
• CDC-5013
• ENMD-0997
• IMID-5013
• Revlimid (Celgene)
• Revlimid (TN)
• Thalidomide analog CC-5013
• Lenalidomide (USAN/INN)
• CC-5013, Revlimid, Lenalidomide
• 3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione
• 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione
• 3-(7-Amino-3-oxo-1H-isoindol-2-yl)-piperidine-2,6-dione
• 3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione
• Lenalidomide (Immunomodulator)
• CC 5013
• Lenalidomide (CC-5013)
• Lenadoamide
• 2,6-Piperidinedione, 3-(4-amino-1,3-dihydro-1-oxo-2H- isoindol-2-yl)-
• NSC 747972
• CHEBI:63791

Reported adverse events

• Neutropenia
• Thrombocytopenia
• DVT
• Thromboembolism
• Abdominal pain
• Arthralgia
• Asthenia
• Back pain
• Bronchitis
• Cardiac failure
• Cataract
• Cellulitis