← SynDRA
GUANFACINE
SynDRA canonical compound SYN0002247 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ADRA2B |
|---|
| Mechanism of action | Adrenergic receptor agonist |
|---|
| Indication | hypertension |
|---|
| Disease area | cardiology |
|---|
All known targets
- ADRA2A
- ADRA2B
- ADRA2C
- ADRA1D
- Adra1a
- CYP3A5
- HCN1
- HCN2
- HCN3
- HCN4
- HTR2A
- HTR2B
Mechanisms of action (all sources)
- Adrenergic receptor agonist
- ADRA2A AGONIST
- Adrenergic receptor alpha-2 agonist
- ADRA2C AGONIST
- ADRA2B AGONIST
- ADRA2A PARTIAL AGONIST
- ADRA2B FULL AGONIST
Drug classes
- Adrenergic alpha2-Agonists
- Central alpha-2 Adrenergic Agonist
- Adrenergic Agents
- Adrenergic Agonists
- Adrenergic alpha-2 Receptor Agonists
- Adrenergic alpha-Agonists
- Antihypertensive Agents
- Cardiovascular Agents
- Neurotransmitter Agents
ATC classes
- C02A · ANTIADRENERGIC AGENTS, CENTRALLY ACTING
Cross-references
Synonyms
- guanfacine hydrochloride
- guanfacine HCl
- guanfacine monohydrochloride
- Guanfacina
- NSC-759121
- Intuniv
- (2,6-dichlorophenylacetyl)-guanidine
- [(2,6-dichlorophenyl)acetyl]guanidine
- [(2,6-Dichlorophenyl)acetyl]guanidine hydrochloride
- 30OMY4G3MK
- A902647
- A918619
- AB01563079_01
- AKOS030255657
- AKOS030526130
- BCP09647
- BDBM81984
- Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-
- BPBio1_000415
- BRD-K32830106-003-03-0
- BRD-K32830106-003-11-3
- BSPBio_000377
- C02AC02
- C07037
- CAS_29110-47-2
- CAS-29110-48-3
- CCG-204609
- CHEBI:5558
- CHEMBL862
- D08031
- DB01018
- DTXCID7026944
- DTXSID9046944
- EINECS 249-442-8
- EN300-243924
- Estulic
- Estulic (Salt/Mix)
Reported adverse events
- Asthenia
- Constipation
- Dizziness
- Fatigue
- Headache
- Insomnia
- Somnolence
- Adverse reaction
- Dry mouth
- Eye disorder
Look up GUANFACINE in the interactive SynDRA portal →