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ETOPOSIDE
SynDRA canonical compound SYN0002320 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | TOP2B |
|---|
| Mechanism of action | Topoisomerase inhibitor |
|---|
| Indication | non-small cell lung cancer (NSCLC) |
|---|
| Disease area | oncology |
|---|
All known targets
- TOP2A
- TOP2B
- ABCB1
- ABCC1
- ABCC2
- ABCC3
- ABCC6
- ABCG2
- ALOX15
- CYP2E1
- CYP3A5
- NR1I2
Mechanisms of action (all sources)
- topoisomerase inhibitor
- TOP2A INHIBITOR
- DNA topoisomerase II inhibitor
- TOP2B INHIBITOR
- Modulator
Drug classes
- Topoisomerase Inhibitors
- Antineoplastic Agents
- Antineoplastic Agents, Phytogenic
- Enzyme Inhibitors
- Topoisomerase II Inhibitors
- Topoisomerase Inhibitor
ATC classes
- L01C · PLANT ALKALOIDS AND OTHER NATURAL PRODUCTS
Cross-references
Synonyms
- etosid
- fytosid
- toposar
- zuyeyidal
- VP-16
- Etoposido
- Etoposidum
- Sintopozid
- NSC-141540
- VP-16-213
- Toposar
- Vepesid
- Etoposide resolution mixture
- VePesid
- trans-Etoposide
- Lastet
- (-)-Etoposide
- Zuyeyidal
- Vepesid J
- Eposin
- Etoposidum [INN-Latin]
- Etoposide (VP16)
- VP 16 (pharmaceutical)
- Etoposido [INN-Spanish]
- Etopophos (phosphate salt)
- 4-Demethylepipodophyllotoxin-beta-D-ethylideneglucoside
- VP 16213
- UNII-6PLQ3CP4P3
- NK 171
- CCRIS 2392
- HSDB 6517
- 4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside)
- EINECS 251-509-1
- Eposide
- Etopol
- Etosid
- Vepeside
- Demethyl EpipodophyllotoxinEthylidine Glucoside
Reported adverse events
- Nausea
- Myelosuppression
- Abdominal pain
- Rash
- Stomatitis
- Hypersensitivity
- Alopecia
- Hypertension
- Leukopenia
- Thrombocytopenia
- Death
- Hypotension
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