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ALENDRONIC ACID

SynDRA canonical compound SYN0002348 — structure-anchored drug synonym record

All known targets

• FDPS
• PTPRS
• ATP6V1A
• FNTB
• FPPS
• Fdps
• Idi1
• PTPN4
• PTPRE

Mechanisms of action (all sources)

• Bone resorption inhibitor
• FDPS INHIBITOR
• Farnesyl diphosphate synthase inhibitor
• FDPS MODULATOR

Drug classes

• Bisphosphonate
• Bone Density Conservation Agents

ATC classes

• M05B · DRUGS AFFECTING BONE STRUCTURE AND MINERALIZATION

Cross-references

• PubChem CID: 2088
• ChEMBL: CHEMBL870
• DrugBank: DB00630
• ChEBI: CHEBI:2567
• KEGG: D00939
• RxNorm: 236083
• PDB: 212
• Wikipedia: Alendronic_acid
• TTD: D09KLR
• LINCS BRD: BRD-K75527158

Synonyms

• alendronate monosodium salt trihydrate
• alendronate sodium trihydrate
• alendronate sodium hydrate
• alendronate
• alendronate sodium
• aminohydroxybutane bisphosphonate
• MK-217
• Acide alendronique
• Acido alendronico
• Alendronate
• Binosto
• Fosamax
• Arendal
• ALENDRONATE SODIUM
• Acidum alendronicum
• Acide alendronique [INN-French]
• Acido alendronico [INN-Spanish]
• Acidum alendronicum [INN-Latin]
• Alendronic acid (INN)
• Alendronic acid [INN:BAN]
• Bisphosphonate, 65
• Fosamax (TN)
• Phosphonic acid, (4-amino-1-hydroxybutylidene)bis
• (4-Amino-1-hydroxybutylidene)bisphosphonic acid
• (4-Amino-1-hydroxybutylidene)diphosphonic acid
• (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid
• (4-amino-1-hydroxybutane-1,1-diyl)bis(phosphonic acid)
• 4-Amino-1-hydroxybutane-1,1-diphosphonate
• 4-Amino-1-hydroxybutane-1,1-diphosphonic Acid
• 4-Amino-1-hydroxybutylidene-1,1-bis(phosphonic acid)
• 4-Amino-1-hydroxybutylidene-1,1-bisphosphonate
• alendronic-acid
• ABDP
• alpha-hydroxy-delta-aminobutylidenediphosphonic acid
• P,P'-(4-Amino-1-hydroxybutylidene)bisphosphonic acid
• Phosphonic acid, P,P'-(4-amino-1-hydroxybutylidene)bis-

Reported adverse events

• Fracture
• Rash
• Stevens-Johnson syndrome
• Headache
• Abdominal pain
• Constipation
• Dizziness
• Dyspepsia
• Flatulence
• Gastritis
• Vomiting
• Nausea