← SynDRA

MIBEFRADIL

SynDRA canonical compound SYN0002377 — structure-anchored drug synonym record

All known targets

• CACNA1H
• CACNA1I
• CACNA1G
• CACNA1C
• CATSPER2
• CATSPER3
• CATSPER1
• CATSPER4
• SCN5A
• SCN9A
• Cacna1a
• SCN2A

Mechanisms of action (all sources)

• T-type calcium channel blocker
• CACNA1H BLOCKER
• Voltage-gated T-type calcium channel blocker
• CACNA1G BLOCKER
• CACNA1I BLOCKER
• CACNA1H INHIBITOR

Drug classes

• Antihypertensive Agents
• Calcium Channel Blockers
• Calcium-Regulating Hormones and Agents
• Cardiovascular Agents
• Cytochrome P-450 CYP1A2 Inhibitors
• Cytochrome P-450 Enzyme Inhibitors
• Enzyme Inhibitors
• Membrane Transport Modulators
• Metabolic Side Effects of Drugs and Substances
• Vasodilator Agents

ATC classes

• C08C · SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS

Cross-references

• PubChem CID: 60663
• ChEMBL: CHEMBL45816
• DrugBank: DB01388
• ChEBI: CHEBI:6920
• KEGG: D05024
• PDB: MWV
• Wikipedia: Mibefradil
• TTD: D0W8XT
• LINCS BRD: BRD-K09549677

Synonyms

• mibefradil dihydrochloride
• posicor
• Ro 40-5967
• Posicor 100
• Posicor 50
• Mibefradil (Cytostatic Checkpoint Therapy, ovarian cancer)
• Mibefradil (Cytostatic Checkpoint Therapy, ovarian cancer), Tau Therapeutics
• Calcium T-channel inhibitor (Cytostatic Checkpoint Therapy, ovarian cancer), Tau Therapeutics
• Mibefradil [INN:BAN]
• Ro 40 5967
• Mibefradil (INN)
• Mibefradil HCl
• [(1S,2S)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-6-fluoro-1-propan-2-yl-3,4-dihydro-1H-naphthalen-2-yl] 2-methoxyacetate
• CHEMBL45816
• CHEBI:6920
• 27B90X776A
• MIBEFRADIL [INN]
• Acetic acid, methoxy-, (1S,2S)-2-[2-[[3-(1H-benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl ester
• Acetic acid, methoxy-, 2-(2-((3-(1H-benzimidazol-2-yl)propyl)methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl ester, (1S-cis)-
• MLS001056800
• Mibefradil dihydrochloride hydrate
• (1S,2S)-2-(2-((3-(1H-benzo[d]imidazol-2-yl)propyl)(methyl)amino)ethyl)-6-fluoro-1-isopropyl-1,2,3,4-tetrahydronaphthalen-2-yl 2-methoxyacetate
• (1S,2S)-2-(2-{[3-(1H-benzimidazol-2-yl)propyl](methyl)amino}ethyl)-6-fluoro-1-(propan-2-yl)-1,2,3,4-tetrahydronaphthalen-2-yl methoxyacetate
• AC1L1TOE
• SMR000326970
• Lopac-M-5441
• Ro 405967
• UNII-27B90X776A
• MIBEFRADIL [MI]
• MIBEFRADIL [VANDF]
• MIBEFRADIL [WHO-DD]
• Lopac0_000748
• SCHEMBL39551
• (1S-cis)-2-(2-((3-(1H-Benzimidazol-2-yl)propyl)methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl methoxyacetate
• 2-(2-((3-(1H-Benzimidazol-2-yl)propyl)methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl methoxyacetate (1S-cis)-
• MIBEFRADILDIHYDROCHLORIDE
• GTPL2522
• DTXSID1023318