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NALBUPHINE
SynDRA canonical compound SYN0002449 — structure-anchored drug synonym record
| Clinical phase | Launched |
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| Approval status | Approved · Rx/OTC |
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| Primary target(s) | OPRM1 |
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| Mechanism of action | Opioid receptor antagonist |
|---|
| Indication | pain relief |
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| Disease area | neurology/psychiatry |
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All known targets
Mechanisms of action (all sources)
- Opioid receptor agonist
- Opioid receptor antagonist
- OPRK1 AGONIST
- Opioid receptors; mu/kappa/delta agonist
- OPRD1 AGONIST
- OPRM1 AGONIST
- OPRK1 MODULATOR
Drug classes
- Analgesics
- Analgesics, Opioid
- Central Nervous System Agents
- Central Nervous System Depressants
- Narcotics
- Peripheral Nervous System Agents
- Sensory System Agents
- Partial Opioid Agonists
- Competitive Opioid Antagonists
- Opioid Agonist/Antagonist
ATC classes
Cross-references
Synonyms
- N-Cyclobutylmethyl-14-hydroxydihydronormorphine
- nalbuphine hydrochloride
- nalbuphine HCl
- Nalbufina
- Intapan
- Nalbuphinum
- Intapan (TN)
- Nalbuphine (INN)
- Nubain (TN)
- (5alpha,6alpha)-17-(cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol
- 17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alpha,14-triol
- PHN-131
- NALBUPHINE HYDROCHLORIDE
- Nalbuphine HCL
- Nubain
- Nalbufina clorhidrato [Spanish]
- Nalbuphine hydrochloride [USAN]
- EN-2234A
- UNII-ZU4275277R
- EINECS 245-549-9
- ZU4275277R
- 17-(Cyclobutylmethyl)-4,5alpha-epoxymorphinan-3,6alpha,14-triol hydrochloride
- Morphinan-3,6,14-triol, 17-(cyclobutylmethyl)-4,5-epoxy-, hydrochloride, (5-alpha,6-alpha)-
- (5alpha,6alpha)-17-(Cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol hydrochloride
- N-Cyclobutylmethyl-14-hydroxydihydronormorphine hydrochloride
- Nalbuphine h
- L2T84IQI2K
- Morphinan-3,6,14-triol, 17-(cyclobutylmethyl)-4,5-epoxy-
- N-Cyclobutylmethyl-4,5alpha-epoxy-3,6alpha,14-morphinantriol
- CHEBI:7454
- DTXCID103345
- RefChem:57230
- NALBUPHINE [INN]
- Nalbuphine (1.0mg/ml in Acetonitrile)
- Nalbufina [DCIT]
- Nalbuphine [INN:BAN]
- Nalbuphinum [INN-Latin]
- UNII-L2T84IQI2K
Reported adverse events
- Depression
- Se
- Death
- Hypertension
- Nervousness
- Abdominal pain
- Allodynia
- Adrenal insufficiency
- Serotonin syndrome
- Overdose
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