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MEVASTATIN

SynDRA canonical compound SYN0002626 — structure-anchored drug synonym record

All known targets

• HMGCR

Mechanisms of action (all sources)

• HMGCR INHIBITOR
• HMGCR ANTAGONIST

Drug classes

• Anti-Bacterial Agents
• Anticholesteremic Agents
• Antifungal Agents
• Hydroxymethylglutaryl-CoA Reductase Inhibitors

Cross-references

• PubChem CID: 64715
• ChEMBL: CHEMBL54440
• DrugBank: DB06693
• ChEBI: 34848
• KEGG: C13963
• PDB: 2UO
• Wikipedia: Mevastatin
• TTD: D0J9GD
• LINCS BRD: BRD-K94441233

Synonyms

• Mevastatine
• Mevastatina
• Compactin
• CS-500
• CS500
• L-637312
• L637312
• ML-236B LACTONE
• ML236B LACTONE
• NSC-281245
• NSC-759322
• NSC281245
• compactin
• ML-236B
• Mevastatinum
• Mevastatinum [INN-Latin]
• Antibiotic ML 236B
• Mevastatin [INN]
• CS 500
• Compactin (penicillium)
• Mevastatine [INN-French]
• UNII-1UQM1K0W9X
• ML 236 B
• Mevastatina [INN-Spanish]
• CCRIS 4505
• 1UQM1K0W9X
• CHEMBL54440
• CHEBI:34848
• [(1S,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate
• Mevastatin (Compactin)
• ML236B
• EC 700-442-0
• NSC 759322
• (1S,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-7-methyl-8-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthyl (S)-2-methylbutyrate
• (1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-methylbutanoate
• (S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) 2-methylbutanoate
• Butanoic acid, 2-methyl-, (1S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, (2S)-
• SMR000336944