HALOTHANE

SynDRA canonical compound SYN0002656 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · OTC
Primary target(s)	CYP2E1 \| GABRA1 \| GABRA2 \| GABRA3 \| GABRA4 \| GABRA5 \| GABRA6 \| GABRB1 \| GABRB2 \| GABRB3 \| GABRD \| GABRE \| GABRG1 \| GABRG2 \| GABRG3 \| GABRP \| GABRQ \| GLRA1 \| GLRB \| KCNK10 \| KCNK12 \| KCNK13 \| KCNK15 \| KCNK18 \| KCNK2 \| KCNK3 \| KCNK9
Mechanism of action	glutamate receptor antagonist
Indication	general anaesthetic
Disease area	neurology/psychiatry

All known targets

KCNK3
KCNK2
KCNK9
KCNK10
KCNK18
GLRB
GLRA1
GABRA1
KCNK13
KCNK12
GABRQ
GABRP

Mechanisms of action (all sources)

GLRA1 POSITIVE MODULATOR
Glycine receptor (alpha-1/beta) positive modulator
GLRB POSITIVE MODULATOR
KCNK10 OPENER
Potassium channel subfamily K member 10 opener
KCNK18 OPENER
Potassium channel subfamily K member 18 opener
KCNK3 OPENER
Potassium channel subfamily K member 3 opener
KCNK9 OPENER
Potassium channel subfamily K member 9 opener
KCNK2 OPENER

Drug classes

Anesthetics
Anesthetics, Inhalation
Central Nervous System Agents
Central Nervous System Depressants

ATC classes

N01A · ANESTHETICS, GENERAL

Cross-references

PubChem CID: 3562
ChEMBL: CHEMBL931
DrugBank: DB01159
ChEBI: CHEBI:5615
KEGG: D00542
Wikipedia: Halothane
TTD: D0D8VE

Synonyms

Look up HALOTHANE in the interactive SynDRA portal →