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RITONAVIR
SynDRA canonical compound SYN0002693 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | CYP3A5 |
|---|
| Mechanism of action | HIV protease inhibitor |
|---|
| Indication | human immunodeficiency virus (HIV-1) |
|---|
| Disease area | infectious disease |
|---|
All known targets
- CYP3A4
- CYP3A5
- CYP2C9
- CYP2D6
- CYP3A7
- CYP1A2
- CYP2B6
- CYP2C19
- CYP2C8
- CYP2E1
- UGT1A1
- SLC47A2
Mechanisms of action (all sources)
- protease inhibitor
- CYP3A4 INHIBITOR
- Cytochrome P450 3A inhibitor
- CYP3A5 INHIBITOR
- CYP3A43 INHIBITOR
- CYP3A7 INHIBITOR
- Inhibitor
- Modulator
- pol INHIBITOR
Drug classes
- HIV Protease Inhibitors
- Protease Inhibitor
- Cytochrome P450 2D6 Inhibitors
- Cytochrome P450 3A4 Inhibitors
- P-Glycoprotein Inhibitors
- Cytochrome P450 2C9 Inducers
- Cytochrome P450 2C19 Inducers
- Cytochrome P450 2B6 Inducers
- Breast Cancer Resistance Protein Inhibitors
- Cytochrome P450 3A Inhibitors
- UDP Glucuronosyltransferases Inducers
- Cytochrome P450 3A Inducers
ATC classes
- J05A · DIRECT ACTING ANTIVIRALS
Cross-references
Synonyms
- ABT538
- ABT-538
- norvir
- Empetus
- Ritomune
- Ritonavirum
- Ritovir
- Viekirax
- Viriton
- A-84538
- ABBOTT-84538
- NSC-693184
- Norvir
- Ritonavir component of kaletra
- Ritonavir component of paxlovid
- Ritonavir component of technivie
- Ritonavir component of viekirax
- Ritonavir component of xiannuoxin
- Ritonavir mylan
- Ritonavir related compounds mixture
- Ombitasvir + paritaprevir + ritonavir
- ABT-267/ABT-450/ritonavir
- ABT-267/ritonavir/ABT-450
- ABT-450/ABT-267/ritonavir
- ABT-450/r + NS5A
- ABT-450/r/ABT-267
- ABT-450/ritonavir/ABT-267
- HOLKIRA PAK
- OBV/PTV/r
- Ombitasvir/ABT 450/ritonavir
- Ombitasvir/ritonavir/ABT-450
- Ombitasvir/ritonavir/veruprevir
- Paritaprevir/ombitasvir/ritonavir
- Ritonavir/ABT 450/ombitasvir
- Ritonavir/ABT-267/ABT-450
- Ritonavir/ABT-450/ABT-267
- Ritonavir/ombitasvir/ABT-450
- Ritonavir/ombitasvir/paritaprevir
Reported adverse events
- Pancreatitis
- Dysgeusia
- Rash
- Hepatotoxicity
- Toxic epidermal necrolysis
- Hypertension
- Stevens-Johnson syndrome
- Myalgia
- Nausea
- Vomiting
- Acne
- Arthralgia
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