GABAPENTIN

SynDRA canonical compound SYN0002697 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · Rx/OTC
Primary target(s)	CACNA2D2
Mechanism of action	Calcium channel blocker
Indication	restless leg syndrome \| seizures \| shingles \| virus herpes simplex (HSV)
Disease area	infectious disease \| neurology/psychiatry

All known targets

CACNA2D1
CACNA2D2
ADORA1
CACNA1B
KCNQ5
KCNQ3
GRIN3A
GRIN1
CACNG6
CACNG7
CACNG8
Cacna2d1

Mechanisms of action (all sources)

Calcium channel blocker
KCNQ3 ACTIVATOR
KCNQ5 ACTIVATOR
Antagonist
CACNA2D1 MODULATOR
CACNA2D2 MODULATOR

Drug classes

Analgesics
Anti-Anxiety Agents
Anticonvulsants
Antimanic Agents
Central Nervous System Agents
Central Nervous System Depressants
Excitatory Amino Acid Antagonists
Neurotransmitter Agents
Peripheral Nervous System Agents
Psychotropic Drugs
Sensory System Agents
Tranquilizing Agents

ATC classes

N02B · OTHER ANALGESICS AND ANTIPYRETICS

Cross-references

PubChem CID: 3446
ChEMBL: CHEMBL940
DrugBank: DB00996
ChEBI: CHEBI:42797
KEGG: D00332
RxNorm: 25480
PDB: GBN
Wikipedia: Gabapentin
TTD: D0J0ZS
LINCS BRD: BRD-K62737565

Synonyms

Reported adverse events

Stevens-Johnson syndrome
Dizziness
Somnolence
Depression
Constipation
Dyspepsia
Nausea
Amblyopia
Amnesia
Ataxia
Diplopia
Fatigue

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