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EPALRESTAT

SynDRA canonical compound SYN0002710 — structure-anchored drug synonym record

All known targets

• AKR1B1
• AKR1A1
• AKR1B10
• Akr1a1
• Akr1b1
• CYP4A11
• SORD

Mechanisms of action (all sources)

• AKR1B1 INHIBITOR
• Aldose reductase inhibitor

Drug classes

• Enzyme Inhibitors

Cross-references

• PubChem CID: 1549120
• ChEMBL: CHEMBL56337
• DrugBank: DB15293
• ChEBI: CHEBI:31539
• KEGG: D01688
• Wikipedia: Epalrestat
• TTD: D03KOZ

Synonyms

• ONO-2235
• eabeth
• sorbistat
• kinedak
• Aldonil
• Aldorin
• Kinedak
• Tanglin
• Epalrestatum
• Ono-2235
• Epalrestat [INN]
• Epalrestatum [Latin]
• ONO 2
• 2-((z)-5-((e)-2-methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid
• UNII-424DV0807X
• C15H13NO3S2
• CHEMBL56337
• 5-((1Z,2E)-2-Methyl-3-phenylpropenylidene)-4-oxo-2-thioxo-3-thiazolidineacetic acid
• CHEBI:31539
• 5-((Z,E)-beta-Methylcinnamylidene)-4-oxo-2-thioxo-3-thiazolidineacetic acid
• 424DV0807X
• Aldorin (TN)
• Kinedak (TN)
• Epalrestat (JAN/INN)
• {5-[(E)-2-Methyl-3-phenyl-prop-2-en-(Z)-ylidene]-4-oxo-2-thioxo-thiazolidin-3-yl}-acetic acid
• {(5Z)-5-[(2E)-2-methyl-3-phenylprop-2-en-1-ylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl}acetic acid
• 2-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid
• 3-carboxymethyl-5-(methyl-3-phenylpropenylidene)rhodanine
• Ono 2235
• RefChem:590902
• DTXCID60210103
• MFCD00865484
• ONO2235
• Ropestatin;
• NCGC00164613-01
• Epalrestat (Standard)
• EPALRESTAT [MI]
• EPALRESTAT [JAN]