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ENTACAPONE
SynDRA canonical compound SYN0002755 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
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| Primary target(s) | COMT |
|---|
| Mechanism of action | catechol O methyltransferase inhibitor |
|---|
| Indication | Parkinson's Disease |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
Mechanisms of action (all sources)
- COMT INHIBITOR
- Catechol O-methyltransferase inhibitor
- catechol O methyltransferase inhibitor
Drug classes
- Anti-Dyskinesia Agents
- Antiparkinson Agents
- Catechol O-Methyltransferase Inhibitors
- Central Nervous System Agents
- Enzyme Inhibitors
- Catechol-O-Methyltransferase Inhibitor
ATC classes
- N04B · DOPAMINERGIC AGENTS
Cross-references
Synonyms
- entacom
- comtess
- Entacapona
- Entacapone orion
- Entacapone teva
- OR-611
- Comtan
- Comtess
- Entacapone component of corbilta
- Entacapone component of levodopa/carbidopa/ orion
- Entacapone component of stalevo
- Entacaponum
- Novartis brand of entacapone
- Orion brand of entacapone
- KB475572
- COM-998
- Comtan (TN)
- Entacapona [INN-Spanish]
- Entacapone [USAN:INN]
- Entacaponum [INN-Latin]
- Stalevo (TN)
- Entacapone (JAN/USAN/INN)
- N,N-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl) acrylamide
- (2E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide
- (E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide
- (E)-2-cyano-3-(3,4-dihydroxy-5-nitro-phenyl)-N,N-diethyl-prop-2-enamide
- (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide
- (E)-alpha-Cyano-N,N-diethyl-3,4-dihydroxy-5-nitrocinnamamide
- 2-Cyano-N,N-diethyl-3-(3,4-dihydroxy-5-nitrophenyl)propenamide
- entacapone (ep monograph)
- STALEVO COMPONENT ENTACAPONE
- LEVODOPA/CARBIDOPA/ENTACAPONE ORION COMPONENT ENTACAPONE
- CORBILTA COMPONENT ENTACAPONE
- entacapone (usp monograph)
- OR 611
- entacapone (usp-rs)
- (E)-Entacapone
- CHEBI:4798
Reported adverse events
- Agitation
- Constipation
- Fatigue
- Nausea
- Anxiety
- Asthenia
- Dizziness
- Dyspepsia
- Flatulence
- Gastritis
- Hyperkinesia
- Hypokinesia
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