ITRACONAZOLE

SynDRA canonical compound SYN0002839 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · Rx/OTC
Primary target(s)	CYP3A5 \| CYP3A7 \| KDR
Mechanism of action	cytochrome P450 inhibitor
Indication	aspergillosis \| blastomycosis \| histoplasmosis \| onychomycosis \| onychomycosis, histoplasmosis, blastomycosis, aspergillosis
Disease area	infectious disease

All known targets

ABCG2
ADRB2
AVPR2
CCR4
CXCR1
CYP3A4
CYP3A5
CYP3A7
CYP51A1
CYP8B1
Candi ERG11
ERG11

Mechanisms of action (all sources)

cytochrome P450 inhibitor
Modulator
ERG11 INHIBITOR

Drug classes

Azole Antifungal
Cytochrome P450 3A4 Inhibitors
P-Glycoprotein Inhibitors
Breast Cancer Resistance Protein Inhibitors
14-alpha Demethylase Inhibitors
Anti-Infective Agents
Antifungal Agents
Cytochrome P-450 CYP3A Inhibitors
Cytochrome P-450 Enzyme Inhibitors
Enzyme Inhibitors
Hormone Antagonists
Metabolic Side Effects of Drugs and Substances

ATC classes

ANTIMYCOTICS FOR SYSTEMIC USE

Cross-references

PubChem CID: 55283
ChEMBL: CHEMBL64391
DrugBank: DB01167
ChEBI: CHEBI:6076
KEGG: D00350
TTD: D0V4IB
LINCS BRD: BRD-A34817987

Synonyms

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