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NALMEFENE
SynDRA canonical compound SYN0002886 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | OPRD1 | OPRK1 | OPRM1 |
|---|
| Mechanism of action | opioid receptor antagonist |
|---|
| Indication | respiratory depression |
|---|
| Disease area | pulmonary |
|---|
All known targets
- OPRD1
- OPRK1
- OPRM1
- Oprd1
- Oprm1
Mechanisms of action (all sources)
- OPRM1 ANTAGONIST
- Mu opioid receptor antagonist
- OPRD1 ANTAGONIST
- Delta opioid receptor antagonist
- OPRK1 PARTIAL AGONIST
- Kappa opioid receptor partial agonist
- opioid receptor antagonist
- OPRK1 ANTAGONIST
Drug classes
- Opioid Antagonists
- Central Nervous System Agents
- Narcotic Antagonists
- Peripheral Nervous System Agents
- Sensory System Agents
- Opioid Antagonist
ATC classes
- N07B · DRUGS USED IN ADDICTIVE DISORDERS
Cross-references
Synonyms
- nalmefene hydrochloride dihydrate
- selincro
- nalmetrene
- 6-desoxy-6-methylenenaltrexone
- nalmefene hydrochloride
- nalmefene HCl
- ORF-11676
- nalmefene hydrochloride hydrate
- Nalmefeno
- Nalmetrene
- JF-1
- JKB-121
- ORF-1167
- SRD-174
- SRD174
- Selincro
- Pruritis treatment, Serentis
- Alcofene
- Arthene
- Cervene
- Cessal
- Incystene
- Nalmefenum
- Nalmetreno
- Nalmetrenum
- Revex
- Soberal
- NIH-10365
- Nalmefeno [INN-Spanish]
- Nalmefenum [INN-Latin]
- Nalmetreno [INN-Spanish]
- Nalmetrenum [INN-Latin]
- Revex (TN)
- Nalmefene (USAN/INN)
- Nalmefene [USAN:BAN:INN]
- (5alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinan-3,14-diol
- (5alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinon-3,14-diol
- (5alpha)-17-(cyclopropylmethyl)-6-methylidene-4,5-epoxymorphinan-3,14-diol
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