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TIAGABINE
SynDRA canonical compound SYN0003258 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SLC6A1 |
|---|
| Mechanism of action | GABA uptake inhibitor |
|---|
| Indication | seizures |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- SLC6A1
- CYP2C19
- Slc6a1
- Slc6a12
Mechanisms of action (all sources)
- GABA uptake inhibitor
- SLC6A1 INHIBITOR
- GABA transporter 1 inhibitor
Drug classes
- Anticonvulsants
- Central Nervous System Agents
- GABA Agents
- GABA Uptake Inhibitors
- Membrane Transport Modulators
- Neurotransmitter Agents
- Neurotransmitter Uptake Inhibitors
- Anti-epileptic Agent
ATC classes
Cross-references
Synonyms
- (R)-Tiagabine
- gabatril
- tiagabine hydrochloride
- tiagabine HCl
- Tiagabina
- Abbott-70569-1
- A-70569-1
- ABBOTT-70569 FREE BASE
- ABBOTT-705691 FREE BASE
- ABT-569 FREE BASE
- NNC-050328 FREE BASE
- NO-050328 FREE BASE
- Gabitril
- Tiagabinum
- Tiagabinum [INN-Latin]
- Tiagabina [INN-Spanish]
- Tiagabine [INN:BAN]
- Tiagabine [INN]
- Abbott-70569
- UNII-Z80I64HMNP
- Tiagabine (INN)
- ABBOTT-70569-1
- Gabitril (TN)
- CHEMBL1027
- Z80I64HMNP
- ABT-569
- CHEBI:9586
- NO-328
- (-)-(R)-1-(4,4-Bis(3-methyl-2-thienyl)-3-butenyl)nipecotic acid
- (R)-1-(4,4-Bis(3-methylthiophen-2-yl)but-3-en-1-yl)piperidine-3-carboxylic acid
- Gabatril
- NO-329
- Tiagabina [INN-Spanish];Tiagabine (INN)
- N-(4,4-di(3-methylthien-2-yl)but-3-enyl)nipecotic acid
- (3R)-1-[4,4-bis(3-methyl-2-thienyl)but-3-en-1-yl]piperidine-3-carboxylic acid
- (3R)-1-[4,4-bis(3-methylthiophen-2-yl)but-3-enyl]piperidine-3-carboxylic acid
- [3H]tiagabine
- (3R)-1-[4,4-bis(3-methylthiophen-2-yl)but-3-en-1-yl]piperidine-3-carboxylic acid
Reported adverse events
- Agitation
- Asthenia
- Ataxia
- Cough
- Depression
- Dizziness
- Hostility
- Insomnia
- Nausea
- Nervousness
- Nystagmus
- Pain
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