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DAPSONE
SynDRA canonical compound SYN0003328 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | DHFR |
|---|
| Mechanism of action | Bacterial antifolate |
|---|
| Indication | dermatitis herpetiformis (DH) | leprosy |
|---|
| Disease area | dermatology | infectious disease |
|---|
All known targets
- DHFR
- CYP3A4
- G6PD
- HTR6
- MPO
- PC DHPS
- PPPK-DHPS
- TAS2R40
- folP1
Mechanisms of action (all sources)
- Bacterial antifolate
- TAS2R40 AGONIST
- Modulator
- folP1 INHIBITOR
Drug classes
- Anti-Bacterial Agents
- Anti-Infective Agents
- Antimalarials
- Antiparasitic Agents
- Antiprotozoal Agents
- Enzyme Inhibitors
- Folic Acid Antagonists
- Leprostatic Agents
- Sulfone
ATC classes
- J04B · DRUGS FOR TREATMENT OF LEPRA
- D10A · ANTI-ACNE PREPARATIONS FOR TOPICAL USE
Cross-references
Synonyms
- diaphenylsulfon
- diaphenylsulfone
- sulphadione
- dapson
- Diaphenylsulfone
- Dapsona
- Dapsonum
- Diaminodiphenylsulfone
- Novophone
- Servidapson
- J04BA02
- NSC-6091
- NSC-6091D
- Aczone
- Atrisone
- Avlosulfon
- Avlosulfone
- Avlosulphone
- Avsulfor
- Croysulfone
- Croysulphone
- DADPS
- DDS
- Dapson
- Diaminodifenilsulfona
- Diaphenylsulfon
- Diaphenylsulphon
- Diaphenylsulphone
- Diphenasone
- Diphone
- Disulone
- Dubronax
- Dubronaz
- Dumitone
- Eporal
- Protogen
- Sulfadione
- Sulfona
Reported adverse events
- Pruritus
- Headache
- Abdominal pain
- Cough
- Erythema
- Influenza
- Nasopharyngitis
- Pharyngitis
- Pyrexia
- Sinusitis
- Suicide attempt
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