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VIGABATRIN
SynDRA canonical compound SYN0003542 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · Rx/OTC |
| Primary target(s) | ABAT |
| Mechanism of action | GABA aminotransferase inhibitor |
| Indication | seizures | spasms |
| Disease area | neurology/psychiatry |
All known targets
Mechanisms of action (all sources)
- GABA aminotransferase inhibitor
- ABAT INHIBITOR
- Gamma-amino-N-butyrate transaminase inhibitor
- ABAT IRREVERSIBLE INHIBITION
- SLC32A1 INHIBITOR
Drug classes
- Anti-epileptic Agent
- Anticonvulsants
- Central Nervous System Agents
- Enzyme Inhibitors
- GABA Agents
- Neurotransmitter Agents
ATC classes
Cross-references
Synonyms
- (+/-)-4-Amino-5-hexenoic acid
- sabril
- vigabatrin hydrochloride
- vigabatrin HCl
- Vigabatrine
- Vigabatrina
- 5-hexenoic acid, 4-amino-
- Gamma-vinyl gaba
- Vigafyde
- Vinyl gamma-aminobutyric acid
- CPP-109
- MDL 71,754
- MDL-71754
- RMI-71754
- Kigabeq
- Sabril
- GVG
- Sabrilex
- Vigabatrinum
- Aventis Brand of Vigabatrin
- Gamma-Vinyl-GABA
- Gamma-Vinyl-gamma-Aminobutyric Acid
- Hoechst Brand of Vigabatrin
- Vigabatrin Aventis Brand
- Vigabatrin Hoechst Brand
- Vigabatrin Yamanouchi Brand
- Vigabatrina [Spanish]
- Vigabatrine [French]
- Vigabatrinum [Latin]
- Yamanouchi Brand of Vigabatrin
- M071754
- V 8261
- V8261_SIGMA
- RMI-71890
- Sabril (TN)
- Sabrilex (TN)
- Hexenoic acid, 4-amino
- Vigabatrin [USAN:BAN:INN]
Reported adverse events
- Vision loss
- Depression
- Rash
- Arthralgia
- Dizziness
- Fatigue
- Headache
- Nausea
- Thirst
- Vomiting
- Abdominal pain
- Acute psychosis
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