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ALOSETRON

SynDRA canonical compound SYN0003772 — structure-anchored drug synonym record

All known targets

• HTR3A
• CYP1A2
• HTR2B
• KCNH2

Mechanisms of action (all sources)

• Serotonin receptor antagonist
• HTR3A ANTAGONIST
• Serotonin 3a (5-HT3a) receptor antagonist

Drug classes

• Gastrointestinal Agents
• Neurotransmitter Agents
• Serotonin Agents
• Serotonin Antagonists
• Serotonin 3 Receptor Antagonists
• Serotonin-3 Receptor Antagonist

ATC classes

• A03A · DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS

Cross-references

• PubChem CID: 2099
• ChEMBL: CHEMBL1110
• DrugBank: DB00969
• ChEBI: CHEBI:53783
• KEGG: D02829
• RxNorm: 85248
• PDB: S7Y
• Wikipedia: Alosetron
• TTD: D06GKN
• LINCS BRD: BRD-K46742498

Synonyms

• alosetron hydrochloride
• alosetron HCl
• alosetron monohydrochloride
• GR68755
• A03AE01
• Lotronex
• Lotrpnex
• ALOSETRON HYDROCHLORIDE
• Alosetron HCl
• Alosetron hydrochloride [USAN]
• Alosetron monohydrochloride
• GR 68755
• GR 68755X
• GR-68755C
• Alosetron (INN)
• Alosetron [INN:BAN]
• Alosetron hydrochloride (USAN)
• Lotronex (TN)
• Lotrpnex (TN)
• 1H-Pyrido(4,3-b)indol-1-one, 2,3,4,5-tetrahydro-5-methyl-2((5-methyl-1H-imidazol-4-yl)methyl)-, monohydrochloride
• 1H-Pyrido(4,3-b)indol-1-one, 2,3,4,5-tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-, monohydrochloride
• 1H-Pyrido[4,3-b]indol-1-one, 2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-, hydrochloride (1:1)
• 1H-Pyrido[4,3-b]indol-1-one, 2,3,4,5-tetrahydro-5-methyl-2-[(5-methyl-1H-imidazol
• 1H-Pyrido[4,3-b]indol-1-one, 2,3,4,5-tetrahydro-5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-(9CI)
• 2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one
• 2,3,4,5-Tetrahydro-5-methyl-2-((5-methylimidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one monohydrochloride
• 2,3,4,5-tetrahydro-5-methyl-2-((5-methylimidazol-4-yl)methyl)-1H-pyridol(4,3-b)indol-1-one monohydrochloride
• 2,3,4,5-tetrahydro-5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H-pyrido[4,3-b]indol-1-one, monohydrochloride
• 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one
• 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one hydrochloride
• 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one
• 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one hydrochloride
• GR-68755
• CHEBI:253342
• alosetronum
• RefChem:58090
• DTXCID4024278
• ALOSETRON [INN]

Reported adverse events

• Abdominal discomfort
• Abdominal pain
• Anxiety
• Arrhythmia
• Burning sensation
• Constipation
• Flatulence
• Headache
• Malaise
• Nausea
• Rash
• Tachyarrhythmia