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AMOXAPINE
SynDRA canonical compound SYN0003790 — structure-anchored drug synonym record
| Clinical phase | Launched |
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| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SLC6A4 |
|---|
| Mechanism of action | Norepinephrine reputake inhibitor |
|---|
| Indication | depression |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- SLC6A2
- SLC6A4
- DRD2
- DRD4
- HTR6
- DRD3
- DRD1
- HTR2A
- HTR2B
- GABRB2
- HTR2C
- HTR3A
Mechanisms of action (all sources)
- Norepinephrine reputake inhibitor
- SLC6A4 INHIBITOR
- Serotonin transporter inhibitor
- SLC6A2 INHIBITOR
- Norepinephrine transporter inhibitor
- DRD2 ANTAGONIST
- Dopamine receptor antagonist
- DRD3 ANTAGONIST
- DRD5 ANTAGONIST
- DRD4 ANTAGONIST
- DRD1 ANTAGONIST
- HTR6 ANTAGONIST
Drug classes
- Adrenergic Agents
- Adrenergic Uptake Inhibitors
- Antidepressive Agents
- Antidepressive Agents, Tricyclic
- Central Nervous System Agents
- Dopamine Agents
- Dopamine Antagonists
- Membrane Transport Modulators
- Neurotransmitter Agents
- Neurotransmitter Uptake Inhibitors
- Psychotropic Drugs
- Selective Serotonin Reuptake Inhibitors
ATC classes
Cross-references
Synonyms
- amoxan
- moxadil
- desmethylloxapine
- Amoxapina
- CL-67,772
- CL-67772
- NSC-759559
- Asendin
- Asendis
- Defanyl
- Amoxan
- Amoxapinum
- Amoxepine
- Ascendin
- Demolox
- Desmethylloxapin
- Desmethylloxapine
- Moxadil
- A-129
- Amoxapina [INN-Spanish]
- Amoxapinum [INN-Latin]
- Asendin (TN)
- Asendis (TN)
- Defanyl (TN)
- Demolox (TN)
- KS-1197
- Moxadil (TN)
- Amoxapine (JP15/USP/INN)
- Amoxapine [USAN:BAN:INN:JAN]
- 2-Chlor-11-(1-piperazinyl)dibenz(b,f)(1,4)oxazepin
- 2-Chloro-11-(1-piperazinyl)-dibenz[b,f][1,4]oxazepine
- 2-Chloro-11-(1-piperazinyl)dibenz(b,f)(1,4)oxazepine
- 2-Chloro-11-(1-piperazinyl)dibenz[b,f][1,4]oxazepine
- 2-chloro-11-(piperazin-1-yl)dibenzo[b,f][1,4]oxazepine
- 2-chloro-11-piperazin-1-yldibenzo[b,f][1,4]oxazepine
- 8-chloro-6-piperazin-1-ylbenzo[b][1,4]benzoxazepine
- loxapine succinate impurity, amoxapine-(usp impurity)
- R63VQ857OT
Reported adverse events
- Neuroleptic malignant syndrome
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