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TELITHROMYCIN

SynDRA canonical compound SYN0003972 — structure-anchored drug synonym record

All known targets

• CYP1A2
• CYP2D6
• CYP3A4
• CYP3A5
• CYP3A7
• KCNH2
• SLCO1B3

Mechanisms of action (all sources)

• bacterial 30S ribosomal subunit inhibitor
• bacterial 30s ribosomal subunit inhibitor, bacterial 50s ribosomal subunit inhibitor
• bacterial 50S ribosomal subunit inhibitor

Drug classes

• Ketolide Antibacterial
• Anti-Bacterial Agents
• Anti-Infective Agents

ATC classes

• J01F · MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS

Cross-references

• PubChem CID: 3002190
• ChEMBL: CHEMBL1136
• DrugBank: DB00976
• ChEBI: CHEBI:29688
• KEGG: D01078
• PDB: TEL
• Wikipedia: Telithromycin
• TTD: D09HNR

Synonyms

• HMR3647
• HMR 3647
• RU 66647
• Ketek
• Telithromycine
• Telitromicina
• Levviax
• HMR-3647
• NSC-758940
• TEL
• RU-66647
• RU66647
• Ketek (TN)
• Telithromycin [USAN:BAN:INN]
• Telithromycin (JAN/USAN/INN)
• (1R,2R,4R,6R,7R,8R,10R,13R,14S)-7-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-13-ethyl-6-methoxy-2,4,6,8,10,14-hexamethyl-17-[4-(4-pyridin-3-ylimidazol-1-yl)butyl]-12,15-dioxa-17-azabicyclo[12.3.0]heptadecane-3,9,11,16-tetrone
• (1R,2R,4R,6R,7R,8R,10S,13R,14S)-7-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-13-ethyl-6-methoxy-2,4,6,8,10,14-hexamethyl-17-[4-(4-pyridin-3-ylimidazol-1-yl)butyl]-12,15-dioxa-17-azabicyclo[12.3.0]heptadecane-3,9,11,16-tetrone
• (1R,2R,4R,6S,7R,8R,10R,13R,14S)-7-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-13-ethyl-6-methoxy-2,4,6,8,10,14-hexamethyl-17-[4-(4-pyridin-3-ylimidazol-1-yl)butyl]-12,15-dioxa-17-azabicyclo[12.3.0]heptadecane-3,9,11,16-tetrone
• (1R,2S,4R,6R,7R,8R,10R,13R,14S)-7-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-13-ethyl-6-methoxy-2,4,6,8,10,14-hexamethyl-17-[4-(4-pyridin-3-ylimidazol-1-yl)butyl]-12,15-dioxa-17-azabicyclo[12.3.0]heptadecane-3,9,11,16-tetrone
• 11,12-Dideoxy-3-des(2,6-dideoxy-3-C,3-O-dimethyl-alpha-L-altropyranosyloxy)-6-O-methyl-3-oxo-12,11-(oxycarbonylimino)-N11-[4-[4-(3-pyridyl)imidazol-1-yl]butyl]erythromycin A
• NSC 758940
• KI8H7H19WL
• telithromycine
• telitromicina
• DTXCID1026455
• telithromycinum
• RefChem:56921
• J01FA15
• UNII-KI8H7H19WL
• MFCD00943561
• CAS-191114-48-4
• C43H65N5O10
• Telithromycin [USAN:INN:BAN]
• HSDB 7359
• NCGC00164575-01
• Telithromycin - 95%
• Telithromycin (Ketek)?
• Telithromycin (Standard)

Reported adverse events

• Dizziness
• Dysgeusia
• Headache
• Hepatitis
• Nausea
• Vomiting