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EPOPROSTENOL
SynDRA canonical compound SYN0004013 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | P2RY12 | PTGER1 | PTGER4 | PTGIR | PTGIS |
|---|
| Mechanism of action | prostacyclin analog |
|---|
| Indication | hypertension |
|---|
| Disease area | cardiology |
|---|
All known targets
- PTGIR
- P2RY12
- PTGER1
- PTGER4
- PTGIS
Mechanisms of action (all sources)
- PTGIR AGONIST
- Prostanoid IP receptor agonist
- prostacyclin analog
- PTGER1 AGONIST
Drug classes
- Prostacycline Vasodilator
- Antihypertensive Agents
- Cardiovascular Agents
- Hematologic Agents
- Platelet Aggregation Inhibitors
ATC classes
- B01A · ANTITHROMBOTIC AGENTS
Cross-references
Synonyms
- epoprostenol sodium
- prostacyclin
- vasocyclin
- Prostaglandin I2
- Prostacyclin
- Pg-i2
- Pgi2
- Pgx
- Prostaglandin i2
- Prostaglandin x
- ACT-385781A
- U-53,217
- U-53217
- Epoprostanol
- Epoprostenolum
- Flolan
- PGX
- Prostacycline
- Prostacyclins
- Vasocyclin
- ProstaglandinI
- Prostaglandin X
- Prostaglandins X
- PGI2
- Prostacyclin I2
- Try-200
- Epoprostenol (TN)
- Epoprostenol [USAN:INN]
- Epoprostenolum [INN-Latin]
- PG-I2
- PGI(sub 2)
- Prostaglandin I(2)
- U 53,217
- Epoprostenol (USAN/INN)
- KB-IV-24
- (5E)-5-[(3aR,4R,5R,6aS)-5-hydroxy-4-[(E,3R)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-ylidene]pentanoic acid
- (5Z)-5-[(3aR,4R,5R,6aS)-5-hydroxy-4-[(E,3S)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-ylidene]pentanoic acid
- (5Z)-5-[(4R,5R)-5-hydroxy-4-[(E,3S)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-ylidene]pentanoic acid
Reported adverse events
- Anxiety
- Headache
- Hyperthyroidism
- Hypotension
- Nausea
- Tachycardia
- Bradycardia
- Chills
- Dizziness
- Eczema
- Flushing
- Myalgia
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