← SynDRA

ATAZANAVIR

SynDRA canonical compound SYN0004202 — structure-anchored drug synonym record

All known targets

• ABCB1
• ABCG2
• CYP1A2
• CYP2C9
• CYP3A4
• HIV PR
• HIV-1 protease
• UGT1A1
• gag-pol
• pol
• protease

Mechanisms of action (all sources)

• protease inhibitor
• Modulator
• pol INHIBITOR

Drug classes

• HIV Protease Inhibitors
• Anti-HIV Agents
• Anti-Infective Agents
• Anti-Retroviral Agents
• Antiviral Agents
• Enzyme Inhibitors
• Protease Inhibitors
• Viral Protease Inhibitors
• Protease Inhibitor
• Cytochrome P450 3A4 Inhibitors
• Cytochrome P450 2C8 Inhibitors
• Cytochrome P450 3A Inhibitors

ATC classes

• J05A · DIRECT ACTING ANTIVIRALS

Cross-references

• PubChem CID: 148192
• ChEMBL: CHEMBL1163
• DrugBank: DB01072
• ChEBI: CHEBI:37924
• KEGG: D01276
• RxNorm: 343047
• PDB: DR7
• Wikipedia: Atazanavir
• TTD: D07IQS
• LINCS BRD: BRD-K09757388

Synonyms

• BMS-232632
• reyataz
• atazanavir sulphate
• atazanavir sulfate
• CGP-73547
• Reyataz
• Latazanavir
• Zrivada
• BMS 232632
• Atazanavir [INN:BAN]
• Atazanavir Base
• UNII-QZU4H47A3S
• HSDB 7339
• Reyataz (TN)
• ATV
• QZU4H47A3S
• CHEMBL1163
• CHEBI:37924
• (3S,8S,9S,12S)-3,12-BIS(1,1-DIMETHYLETHYL)-8-HYDROXY-4,11-DIOXO-9-(PHENYLMETHYL)-6-[[4-(2-PYRIDINYL)PHENYL]METHYL]-2,5,6,10,13-PENTAAZATETRADECANEDIOIC ACID DIMETHYL ESTER
• NCGC00182552-01
• AK174307
• DSSTox_CID_28617
• DSSTox_RID_82887
• DSSTox_GSID_48691
• DR7
• atazanavirum
• ATZ
• Atazanavir (INN)
• Reyataz, BMS-232632, Atazanavir
• Reyataz(TM) (*1:1 sulfate*)
• Dimethyl (3S,8S,9S,12S)-9-benzyl-3,12-di-tert-butyl-8-hydroxy-4,11-dioxo-6-[4-(2-pyridyl)benzyl]-2,5,6,10,13-pentaazatetradecanedioate
• METHYL [(1S,4S,5S,10S)-4-BENZYL-1,10-DI-TERT-BUTYL-5-HYDROXY-2,9,12-TRIOXO-7-(4-PYRIDIN-2-YLBENZYL)-13-OXA-3,7,8,11-TETRAAZATETRADEC-1-YL]CARBAMATE
• Methyl N-[(2S)-1-[2-[(2S,3S)-2-hydroxy-3-[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-4-phenylbutyl]-2-[(4-pyridin-2-ylphenyl)methyl]hydrazinyl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate
• (2S)-N-(3-{[(2S)-2-(Methoxycarbonylamino)-3,3-dimethylbutanoylamino][(4-(2-pyridyl)phenyl)methyl]amino}(1S,2S)-2-hydroxy-1-benzylpropyl)-2-(methoxycarbonylamino)-3,3-dimethylbutanamide
• DTXCID5028617
• RefChem:54330
• J05AE08
• ATAZANAVIR [INN]

Reported adverse events

• Rash
• Jaundice
• Nausea
• Abdominal pain
• Dizziness
• Headache
• Insomnia
• Myalgia
• Vomiting
• Lipase
• Depression
• Hepatitis