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NEFLAMAPIMOD

SynDRA canonical compound SYN0004309 — structure-anchored drug synonym record

All known targets

• MAPK14
• MAPK11
• MAPK12

Mechanisms of action (all sources)

• MAPK14 INHIBITOR
• MAP kinase p38 alpha inhibitor
• MAPK11 INHIBITOR
• MAPK12 INHIBITOR

Cross-references

• PubChem CID: 3038525
• ChEMBL: CHEMBL119385
• DrugBank: DB07138
• ChEBI: 90528
• KEGG: D10959
• PDB: 52P
• TTD: D02NNV
• LINCS BRD: BRD-K91900765

Synonyms

• VX-745
• 745
• NEFLAMAPIMOD (VX-745)
• VD-31
• VD-31,745
• VD-31745
• VRT-031745
• VX745
• VX 745
• 5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido[1,6-b]pyridazin-6-one
• UNII-TYL52QM320
• TYL52QM320
• CHEBI:90528
• 5-(2,6-dichlorophenyl)-2-(2,4-difluorophenylthio)-6H-pyrimido[1,6-b]pyridazin-6-one
• 5-(2,6-dichlorophenyl)-2-(2,4-difluorophenyl)sulfanylpyrimido[1,6-b]pyridazin-6-one
• Neflamapimod (USAN)
• Neflamapimod [USAN]
• AK-44905
• C19H9Cl2F2N3OS
• 5-(2,6-Dichlorophenyl)-2-[(2,4-Difluorophenyl)sulfanyl]-6h-Pyrimido[1,6-B]pyridazin-6-One
• VX745, VX-745
• 5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido(1,6-b)pyridazin-6-one
• Vertex 745 (VX745)
• neflamapimodum
• RefChem:832136
• MFCD09834070
• Kinome_3767
• Neflamapimod (USAN/INN)
• NEFLAMAPIMOD [INN]
• MLS006010281
• NEFLAMAPIMOD [WHO-DD]
• SCHEMBL156367
• GTPL5719
• orb1301083
• SCHEMBL29396525
• BDBM15244
• cid_3038525
• EX-A854
• GLXC-05950