PHENYLEPHRINE

SynDRA canonical compound SYN0004629 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · Rx/OTC
Primary target(s)	ADRA1A
Mechanism of action	Adrenergic receptor agonist
Indication	hemorrhoids \| hypotension \| nasal congestion
Disease area	cardiology \| gastroenterology \| otolaryngology

All known targets

ADRA1A
ADRA1B
ADRA1D
ADRA2A
ADRA2B
ADRA2C
Adra1a
Adra1b
Adra1d
Adra2a
Adra2b
Adra2c

Mechanisms of action (all sources)

Adrenergic receptor agonist
ADRA1A AGONIST
Adrenergic receptor alpha-1 agonist
ADRA1D AGONIST
ADRA1B AGONIST
DRD2 AGONIST

Drug classes

Adrenergic alpha1-Agonists
Adrenergic Agents
Adrenergic Agonists
Adrenergic alpha-1 Receptor Agonists
Adrenergic alpha-Agonists
Cardiotonic Agents
Cardiovascular Agents
Mydriatics
Nasal Decongestants
Neurotransmitter Agents
Peripheral Nervous System Agents
Protective Agents

ATC classes

R01A · DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01B · NASAL DECONGESTANTS FOR SYSTEMIC USE
S01F · MYDRIATICS AND CYCLOPLEGICS
S01G · DECONGESTANTS AND ANTIALLERGICS
C01C · CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
C05A · AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE

Cross-references

PubChem CID: 6041
ChEMBL: CHEMBL1215
DrugBank: DB00388
ChEBI: CHEBI:8093
KEGG: D00511
RxNorm: 8163
Wikipedia: Phenylephrine
TTD: D0O6IU
LINCS BRD: BRD-K73381542

Synonyms

Reported adverse events

Hypertension
Bradycardia
Hypertensive crisis
Nausea
Eye pain
Cardiac disorder
Dry mouth
Tachycardia
Asthma
Dermatitis
Hallucination
Leukopenia

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