← SynDRA

TOLVAPTAN

SynDRA canonical compound SYN0004733 — structure-anchored drug synonym record

All known targets

• AVPR2
• AVPR1A
• Avpr1a
• Avpr2

Mechanisms of action (all sources)

• Vasopressin receptor antagonist
• AVPR2 ANTAGONIST
• Vasopressin V2 receptor antagonist
• AVPR1A ANTAGONIST

Drug classes

• Antidiuretic Hormone Receptor Antagonists
• Natriuretic Agents
• Vasopressin V2 Receptor Antagonists
• Vasopressin V2 Receptor Antagonist

ATC classes

• C03X · OTHER DIURETICS

Cross-references

• PubChem CID: 216237
• ChEMBL: CHEMBL344159
• DrugBank: DB06212
• ChEBI: CHEBI:32246
• KEGG: D01213
• RxNorm: 358257
• Wikipedia: Tolvaptan
• TTD: D03KZM
• LINCS BRD: BRD-A82035391

Synonyms

• OPC-41061
• jinarc
• samsca
• tolvaptan sodium phosphate
• OPC-41061(TOLVAPTAN)
• Jinarc
• Jynarque
• Samsca
• Tolvaptan accord
• Benzazepine derivative, 32
• Samsca (TN)
• N-[4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)-3-methylphenyl]-2-methylbenzamide
• (-)-4'-((7-Chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl)-o-tolu-m-toluidide
• 7-Chloro-5-hydroxy-1-(2-methyl-4-(2-methylbenzoylamino)benzoyl)2,3,4,5-tetrahydro-1H-1-benzazepine
• JYNARQUE
• OPC 41061
• CHEBI:32246
• DTXCID9028706
• tolvaptanum
• RefChem:56517
• C03XA01
• OPC41061
• (R)-(+)-Tolvaptan
• MFCD09838782
• Tolvaptan (OPC-41061)
• C26H25ClN2O3
• NCGC00183001-01
• (S)-(-)-Tolvaptan
• UNII-21G72T1950
• benzazepine derivative, 32
• Tolvaptan [USAN:INN:BAN]
• Tolvaptan?
• HSDB 8196
• Tolvaptan [INN]
• Tolvaptan (Standard)
• TOLVAPTAN [JAN]
• TOLVAPTAN [MI]
• TOLVAPTAN [USAN]

Reported adverse events

• Acute liver failure
• Thirst
• Asthenia
• Dehydration
• Dry mouth
• Constipation
• Pollakiuria
• Pyrexia
• Dizziness
• Hypersensitivity
• Rhabdomyolysis
• Cerebrovascular accident