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ADAPALENE
SynDRA canonical compound SYN0004947 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | RARG |
|---|
| Mechanism of action | Retinoid receptor agonist |
|---|
| Indication | acne vulgaris (AV) |
|---|
| Disease area | dermatology |
|---|
All known targets
- RARA
- RARB
- RARG
- GLRA1
- GOT1
- RXRA
- RXRB
- RXRG
Mechanisms of action (all sources)
- Retinoid receptor agonist
- RARG AGONIST
- Retinoic acid receptor agonist
- RARB AGONIST
- RARA AGONIST
Drug classes
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antirheumatic Agents
- Dermatologic Agents
- Peripheral Nervous System Agents
- Sensory System Agents
- Retinoid
ATC classes
- D10A · ANTI-ACNE PREPARATIONS FOR TOPICAL USE
Cross-references
Synonyms
- differin
- Adapaleno
- CD-271
- Adapalene component of cabtreo
- Adapalene component of epiduo
- Adapalene component of idp-126
- Differin
- Adaferin
- Adapalenum
- Differine
- CD271
- Adaferin (TN)
- Adapaleno [INN-Spanish]
- Adapalenum [INN-Latin]
- Differin (TN)
- Differin, Adapalene
- KS-1196
- Adapalene [USAN:BAN:INN]
- Adapalene (JAN/USAN/INN)
- 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid
- 6-(3-adamantan-1-yl-4-methoxyphenyl)naphthalene-2-carboxylic acid
- 6-[3-(1-adamantyl)-4-methoxyphenyl]naphthalene-2-carboxylic acid
- 6-[3-(adamantan-1-yl)-4-methoxyphenyl]-2-naphthoic acid
- 6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoic acid
- 6-[3-(1-Adamantyl)-4-methoxyphenyl]-2-naphthoic acid
- MFCD03106112
- 6-[3-(1-adamantyl)-4-methoxy-phenyl]naphthalene-2-carboxylic acid
- CHEMBL1265
- 6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid
- CHEBI:31174
- 1L4806J2QF
- 6-[3-(adamantan-1-yl)-4-methoxyphenyl]naphthalene-2-carboxylic acid
- NCGC00164617-01
- Adapalen
- 2-Naphthalenecarboxylic acid, 6-(4-methoxy-3-tricyclo(3.3.1.1(sup 3,7))dec-1-ylphenyl)-
- Differin Gel
- CAS-106685-40-9
Reported adverse events
- Erythema
- Skin irritation
- Pruritus
- Eczema
- Skin burning sensation
- Hypersensitivity
- Dermatitis
- Dry skin
- Application site irritation
- Application site burn
- Dermatitis atopic
- Sunburn
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