ROTIGOTINE

SynDRA canonical compound SYN0005153 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · Rx/OTC
Primary target(s)	DRD5
Mechanism of action	Dopamine receptor agonist
Indication	Parkinson's Disease \| restless leg syndrome
Disease area	neurology/psychiatry

All known targets

DRD2
DRD3
DRD4
DRD1
DRD5
ADRA2B
HTR1A

Mechanisms of action (all sources)

Dopamine receptor agonist
DRD2 AGONIST
D2-like dopamine receptor agonist
DRD3 AGONIST
DRD4 AGONIST

Drug classes

Dopamine Agonists
Dopamine Agents
Neurotransmitter Agents
Nonergot Dopamine Agonist

ATC classes

N04B · DOPAMINERGIC AGENTS

Cross-references

PubChem CID: 59227
ChEMBL: CHEMBL1303
DrugBank: DB05271
ChEBI: CHEBI:135351
KEGG: D05768
RxNorm: 616739
PDB: R5F
Wikipedia: Rotigotine
TTD: D09OQV
LINCS BRD: BRD-K91111634

Synonyms

neupro
leganto
(S)-(-)-Rotigotine
Rotigotina
Leganto
SPM-962
Neupro
(S)-6-(propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol
(6S)-rotigotine
UNII-87T4T8BO2E
(6S)-6-[propyl(2-thiophen-2-ylethyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol
N-0923
CHEMBL1303
87T4T8BO2E
99755-59-6 (free base)
(6S)-6-(Propyl(2-(2-thienyl)ethyl)amino)-5,6,7,8-tetrahydro-1-naphthalenol
NCGC00168748-01
Rotigotine CDS Patch
(6s)-5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol
DSSTox_CID_26772
DSSTox_RID_81893
DSSTox_GSID_46772
C19H25NOS
Rotigotine CDS
(S)-5,6,7,8-Tetrahydro-6-(propyl(2-(2-thienyl)ethyl)amino)-1-naphthol
(S)-6-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-5,6,7,8-tetrahydro-naphthalen-1-ol
CAS-99755-59-6
Neupro (TN)
Rotigotine [USAN:INN:BAN]
(S)-5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthol
(S)-6-[Propyl[2-(thiophen-2-yl)ethyl]amino]-5,6,7,8-tetrahydronaphthalen-1-ol
SPM-936
SPM-937
PubChem16423
(-)-(S)-5,6,7,8-Tetrahydro-6-(propyl(2-(2-thienyl)ethyl)amino)-1-naphthol
GTPL941
cc-129
Rotigotine (JAN/USAN/INN)

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