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SPARSENTAN
SynDRA canonical compound SYN0005549 — structure-anchored drug synonym record
| Clinical phase | Phase 3 |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | AGTR1 | EDNRA |
|---|
| Mechanism of action | angiotensin receptor antagonist |
|---|
All known targets
Mechanisms of action (all sources)
- EDNRA ANTAGONIST
- Endothelin receptor ET-A antagonist
- AGTR1 ANTAGONIST
- Type-1 angiotensin II receptor antagonist
- angiotensin receptor antagonist
Drug classes
- Endothelin Receptor Antagonists
- Angiotensin 2 Receptor Blocker
- Endothelin Receptor Antagonist
- Angiotensin 2 Type 1 Receptor Antagonists
- P-Glycoprotein Inhibitors
- Cytochrome P450 2C9 Inducers
- Cytochrome P450 2C19 Inducers
- Cytochrome P450 2B6 Inducers
- Breast Cancer Resistance Protein Inhibitors
ATC classes
- C09X · OTHER AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
Cross-references
Synonyms
- filspari
- PS433540
- RE-021
- Esparsentan
- Filspari
- PS-433540
- UNII-9242RO5URM
- CHEMBL539423
- 9242RO5URM
- BMS-346567
- retrophin
- Sparsentan [USAN]
- compound 7 [PMID 15634011]
- PS 33540
- Sparsentan (RE-021)
- Sparsentan(PS433540)
- SCHEMBL535109
- GTPL8448
- BCP23969
- BDBM50175523
- SB16876
- DB12548
- CS-7947
- DARA-a (Dual Acting Receptor Antagonist of angiotension and endothelin receptors)
- HY-17621
- L023324
- 4'-((2-butyl-4-oxo-1,3-diazaspiro[44]non-1-en-3-yl)methyl)-N-(4,5-dimethylisoxazol-3-yl)-2'-(ethoxymethyl)-[1,1'-biphenyl]-2-sulfonamide
- DARA
- PS 433540
- FILSPARI
- esparsentan
- sparsentanum
- RefChem:56752
- RE 201
- MFCD16628036
- Spashentan
- C32H40N4O5S
- Filspari (TN)
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