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FULVESTRANT
SynDRA canonical compound SYN0005617 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · Rx/OTC |
| Primary target(s) | ESR1 |
| Mechanism of action | Estrogen receptor antagonist |
| Indication | breast cancer |
| Disease area | oncology |
All known targets
- ESR1
- EPHX2
- ESR2
- GPER1
- ESRRA
- Esr1
- NR1H4
- NR1I2
- PGR
- SIRT5
- bla; blaT-3; blaT-4;
Mechanisms of action (all sources)
- ESR1 ANTAGONIST
- ESR1 DEGRADER
- ESR2 ANTAGONIST
Drug classes
- Estrogen Receptor Antagonists
- Selective Estrogen Receptor Modulators
- Estrogen Receptor Antagonist
- Antineoplastic Agents
- Antineoplastic Agents, Hormonal
- Estrogen Antagonists
- Hormone Antagonists
ATC classes
- L02B · HORMONE ANTAGONISTS AND RELATED AGENTS
Cross-references
Synonyms
- ZD9238
- faslodex
- ICI 182,780
- ICI-182780
- NSC-759879
- ZD-9238
- Faslodex
- Fulvestrant mylan
- AstraZeneca brand of fulvestrant
- Fulvestrant [USAN]
- Ici 182780
- ZD-182780
- ZM-182780
- Faslodex (TN)
- Faslodex(ICI 182,780)
- Faslodex, ICI 182780, Fulvestrant
- Fulvestrant (JAN/USAN/INN)
- (7R,13S,17S)-13-methyl-7-(9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
- (7R,8R,9S,13S,14S,17S)-13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
- (7R,8S,9S,13S,14S,17S)-13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl) nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
- (7alpha,17beta)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1,3,5(10)-triene-3,17-diol
- 7-(9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl)estra-1,3,5(10)-triene-3,17-diol
- 7alpha-(9-((4,4,5,5,5,-Pentafluoropentyl)sulfinyl)nonyl)estra-1,3,5(10)-triene-3,17beta-diol
- 7alpha-(9-((4,4,5,5,5-Pentafluoropentyl)sulfinyl)nonyl)estra-1,3,5(10)-triene-3,17beta-diol
- 7alpha-[9[(4,4,5,5,5-Pentafluropentyl)sulfinyl]nonyl]-estra-1,3,5(10)-triene-3, 17 beta diol
- ICI
- ZD 9238
- Fulvestrant (Faslodex)
- CHEMBL1358
- (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)sulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
- CHEBI:31638
- 22X328QOC4
- NSC 759879
- Estra-1,3,5(10)-triene-3,17-diol, 7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]-, (7alpha,17beta)-
- C32H47F5O3S
- (7alpha,17beta)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17-diol
- Estra-1,3,5(10)-triene-3,17-diol, 7-(9-((4,4,5,5,5-pentafluoropentyl)sulfinyl)nonyl)-, (7alpha,17beta)-
- CAS-129453-61-8
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