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ABACAVIR

SynDRA canonical compound SYN0005878 — structure-anchored drug synonym record

All known targets

• HIV RT
• gag-pol
• pol
• reverse transcriptas

Mechanisms of action (all sources)

• nucleoside reverse transcriptase inhibitor
• Inhibitor
• pol INHIBITOR

Drug classes

• Nucleoside Reverse Transcriptase Inhibitors
• Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor
• Anti-HIV Agents
• Anti-Infective Agents
• Anti-Retroviral Agents
• Antiviral Agents
• Enzyme Inhibitors
• Nucleic Acid Synthesis Inhibitors
• Reverse Transcriptase Inhibitors
• Cytochrome P450 1A1 Inhibitors

ATC classes

• J05A · DIRECT ACTING ANTIVIRALS

Cross-references

• PubChem CID: 441300
• ChEMBL: CHEMBL1380
• DrugBank: DB01048
• ChEBI: CHEBI:421707
• KEGG: D00891
• RxNorm: 190521
• PDB: 1KX
• Wikipedia: Abacavir
• TTD: D0A4IJ

Synonyms

• 1592U89
• abacavir sulfate
• ziagen
• abacavir succinate
• Avacavir
• Epzicom
• NSC-742406
• Ziagen
• Trizivir
• Abacavir [INN]
• Abacavir (INN)
• Ziagen (TN)
• Ziagen (TM)(*Succinate salt*)
• [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol
• {(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol
• (+/-)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol
• (+/-)-Abacavir
• (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol
• ABC
• NSC 742406
• WR2TIP26VS
• CHEBI:421707
• abacavirum
• (+)-abacavir sulfate
• RefChem:551202
• (1R,4S)-abacavir sulfate
• J05AF06
• DTXCID601478426
• MFCD00903850
• Abacavir (1.0 mg/mL in Methanol)
• Abacavir [INN:BAN]
• UNII-WR2TIP26VS
• NSC742406
• NCGC00164560-01
• Abacavir (Standard)
• ABACAVIR [MI]
• ABACAVIR [VANDF]
• AVACAVIR [VANDF]

Reported adverse events

• Hypersensitivity
• Lactic acidosis
• Hepatomegaly
• Lactic acid
• Hepatitis
• Hepatitis B
• Acidosis
• P
• Se
• Myopathy
• DIC
• UTI