EX-527

SynDRA canonical compound SYN0006016 — structure-anchored drug synonym record

Clinical phase	Phase 2
Primary target(s)	SIRT1
Mechanism of action	SIRT inhibitor

All known targets

SIRT1
BDKRB2

Mechanisms of action (all sources)

BDKRB2 ANTAGONIST
SIRT inhibitor
SIRT1 INHIBITOR

Cross-references

PubChem CID: 5113032
ChEMBL: CHEMBL382277
ChEBI: 90369
TTD: D0E3LP

Synonyms

SEN-196
SEN-0014196
SIRT1 inhibitors (Huntingtons disease), Elixir/Siena
Sirtuin-1 inhibitors (oral, Huntington's disease), Elixir/Siena
6-chloro-2,3,4,4a,9,9a-hexahydro-1H-carbazole-1-carboxamide
SCHEMBL18134580
SCHEMBL29375918
BDBM50178783
DB-359370
SCHEMBL1649974
FC176241
L001604

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