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DAUNORUBICIN

SynDRA canonical compound SYN0006067 — structure-anchored drug synonym record

All known targets

• TOP2A
• ABCB1
• ABCC1
• ABCC6
• ABCG2
• HDAC1
• HDAC6
• HDAC8
• MMP2
• TOP2B

Mechanisms of action (all sources)

• RNA synthesis inhibitor
• topoisomerase inhibitor
• TOP2A INHIBITOR
• DNA topoisomerase II alpha inhibitor

Drug classes

• Topoisomerase Inhibitors
• Anthracycline Topoisomerase Inhibitor
• Antibiotics, Antineoplastic
• Antineoplastic Agents
• Enzyme Inhibitors
• Topoisomerase II Inhibitors

ATC classes

• L01D · CYTOTOXIC ANTIBIOTICS AND RELATED SUBSTANCES
• OTHER ANTINEOPLASTIC AGENTS

Cross-references

• PubChem CID: 30323
• ChEMBL: CHEMBL178
• DrugBank: DB00694
• ChEBI: CHEBI:41977
• KEGG: D01264
• RxNorm: 3109
• PDB: DM1
• Wikipedia: Daunorubicin
• TTD: D01XWG
• LINCS BRD: BRD-K43389675

Synonyms

• acetyladriamycin
• cerubidin
• daunoblastina
• daunomycine
• daunorubicine
• Leukaemomycin C
• rubidomycin
• daunorubicin hydrochloride
• daunorubicin citrate
• daunorubicin HCl
• Daunorubicine
• Daunorubicina
• Daunomycin
• FI-6339
• NSC-83142
• RP-13057
• Daunorubicin component of vyxeos
• Daunoxome
• Epirubicin hydrochloride impurity, daunorubicin-
• Valrubicin impurity, daunorubicin
• Rubidomycin
• Cerubidine
• Acetyladriamycin
• Daunorubicinum
• Daunarubicinum
• Daunorrubicina
• Daunamycin
• Cerubidin
• DaunoXome
• Rubomycin C
• (+)-Daunomycin
• Daunoblastin
• Anthracyline
• Rubomycin
• Daunorubicinum [INN-Latin]
• RP 13057
• Daunorubicin [INN:BAN]
• RCRA waste no U059

Reported adverse events

• Abdominal pain
• Anxiety
• Arrhythmia
• Cardiac arrest
• Chest pain
• Chills
• Constipation
• Cough
• Delirium
• Dizziness
• Dyspepsia
• Fatigue