← SynDRA

APRATASTAT

SynDRA canonical compound SYN0006140 — structure-anchored drug synonym record

All known targets

• ADAM17
• MMP13
• MMP1
• MMP9

Mechanisms of action (all sources)

• MMP13 INHIBITOR
• Matrix metalloproteinase 13 inhibitor
• ADAM17 INHIBITOR
• matrix metalloprotease inhibitor
• tumor necrosis factor production inhibitor
• MMP1 INHIBITOR
• MMP13 MODULATOR
• ADAM17 MODULATOR

Cross-references

• PubChem CID: 11452716
• ChEMBL: CHEMBL206815
• DrugBank: DB13020
• ChEBI: 177520
• KEGG: D08859
• TTD: D0HG5M

Synonyms

• TMI-005
• TMI-05
• TMI 005
• UNII-C6BZ5263BJ
• C6BZ5263BJ
• CHEMBL206815
• Apratastat [USAN:INN]
• Apratastat (USAN/INN)
• MLS006010301
• SCHEMBL2834310
• GTPL6482
• TMI005
• Apratastat, &gt
• MolPort-021-805-014
• BCPP000041
• ZINC28571311
• BDBM50181008
• DB13020
• API0013699
• compound 5h [PMID: 16426848]
• SMR004701369
• 4CA-0170
• D08859
• 3-Thiomorpholinecarboxamide,N-hydroxy-4-[[4-[(4-hydroxy-2-butyn-1-yl)oxy]phenyl]sulfonyl]-2,2-dimethyl-,(3S)-
• TMI-1
• Dual TACE/MMP-13 inhibitors (inflammation), Wyeth
• Dual TACE/MMP-13 inhibitors (rheumatoid arthritis), Wyeth
• Dual TACE/MMP-13 inhibitors, Wyeth-Ayerst
• apratastatum
• RefChem:558431
• DTXCID001511187
• Apratastat [USAN]
• APRATASTAT [INN]
• orb1707645
• Apratastat, >=98% (HPLC)
• C17H22N2O6S2
• CHEBI:177520
• MLA40551
• EX-A14846