← SynDRA

TRIPTOLIDE

SynDRA canonical compound SYN0006185 — structure-anchored drug synonym record

All known targets

• CYP2C19
• NFKB1; NFKB2; RELA; RELB; REL
• RELA

Mechanisms of action (all sources)

• RNA polymerase inhibitor
• Inhibitor

Drug classes

• Antineoplastic Agents, Alkylating
• Antispermatogenic Agents
• Immunosuppressive Agents

Cross-references

• PubChem CID: 107985
• ChEMBL: CHEMBL463763
• DrugBank: DB12025
• ChEBI: 9747
• KEGG: C09204
• PDB: TLI
• Wikipedia: Triptolide
• TTD: D0I6LH
• LINCS BRD: BRD-K39484304

Synonyms

• NSC-163062
• Triptolid
• PG490
• UNII-19ALD1S53J
• NSC 163062
• CHEMBL463763
• CHEBI:9747
• 19ALD1S53J
• C20H24O6
• PG 490
• CPD000466307
• Triptolide, Tripterygium wilfordii
• (-)-Triptolide
• Trisoxireno(4b,5:6,7:8a,9)phenanthro(1,2-c)furan-1(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-
• SMR000466307
• NSC163062
• Triptolide, 1
• Triptolide(PG490)/
• AC1Q6AXN
• BSPBio_001595
• KBioGR_000315
• KBioSS_000315
• PG-490
• (1S,2S,4S,5S,7R,8R,9S,11S,13S)-8-hydroxy-1-methyl-7-propan-2-yl-3,6,10,16-tetraoxaheptacyclo[11.7.0.02,4.02,9.05,7.09,11.014,18]icos-14(18)-en-17-one
• (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-6-hydroxy-8b-methyl-6a-(propan-2-yl)-3b,4,4a,6,6a,7a,7b,8b,9,10-decahydrotrisoxireno[6,7:8a,9:4b,5]phenanthro[1,2-c]furan-1(3H)-one
• (5bS,6aS,7aS,8R,8aR,9aS,9bS,10aS,10bS)-8-Hydroxy-8a-isopropyl-10b-methyl-1,5,5b,6,6a,8,8a,9a,9b,10b-decahydrotris(oxireno)[2',3':4b,5;2'',3'':6,7;2''',3''':8a,9]phenanthro[1,2-c]furan-3(2H)-one
• (6aS,7aS,8R,8aR,9aS,9bS,10aS,10bS)-8-hydroxy-8a-isopropyl-10b-methyl-1,5,5b,6,6a,8,8a,9a,9b,10b-decahydrotris(oxireno)[2',3':4b,5;2'',3'':6,7;2''',3''':8a,9]phenanthro[1,2-c]furan-3(2H)-one.
• (3BS,4AS,5AS,6R,6AR,7AS,7BS,8AS,8BS)-3B,4,4A,6,6A,7A,7B,8B,9,10-DECAHYDRO-6-HYDROXY-8B-METHYL-6A-(1-METHYLETHYL)TRISOXIRENO(4B,5:6,7:8A,9)PHENANTHRO(1,2-C)FURAN-1(3H)-ONE
• (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-3b,4,4a,6,6a,7a,7b,8b,9,10-Decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one
• Trisoxireno[6,7:8a,9:4b,5]phenanthro[1,2-c]furan-1(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-
• MFCD00210565
• TRIPTOLIDE [MI]
• TRIPTOLIDE [WHO-DD]
• MLS000759410
• MLS001424107
• MLS006010844
• SCHEMBL413634
• DTXSID5041144