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DIAZOXIDE
SynDRA canonical compound SYN0006421 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | KCNJ11 |
|---|
| Mechanism of action | Potassium channel activator |
|---|
| Indication | hypoglycemia |
|---|
| Disease area | endocrinology |
|---|
All known targets
- KCNJ11
- KCNJ8
- ABCC8
- ATP1A1
- CA1
- CA2
- KCNMA1
- Kcnj11
- NAMPT
- SLC12A3
Mechanisms of action (all sources)
- Potassium channel activator
- KCNJ11 OPENER
- Potassium channel, inwardly rectifying, subfamily J, member 11 opener
- KCNJ8 OPENER
- Potassium channel, inwardly rectifying, subfamily J, member 8 opener
- ABCC8 OPENER
Drug classes
- Antihypertensive Agents
- Cardiovascular Agents
- Vasodilator Agents
ATC classes
- V03A · ALL OTHER THERAPEUTIC PRODUCTS
- C02D · ARTERIOLAR SMOOTH MUSCLE, AGENTS ACTING ON
Cross-references
Synonyms
- dizoxide
- hyperstat
- hypertonalum
- proglicem
- Diazoxido
- Diazoxidum
- Eudemine injection
- Hypertonalum
- NSC-64198
- NSC-76130
- SCH-6783
- SRG-95213
- Eudemine
- Eudimine
- Hyperstat
- Mutabase
- Proglycem
- Aroglycem
- Diazossido
- Dizoxide
- Proglicem
- Diazossido [DCIT]
- Diazossido [Italian]
- D 9035
- Sch-6783
- Diazoxido [INN-Spanish]
- Diazoxidum [INN-Latin]
- Hyperstat (TN)
- Diazoxide [USAN:INN:BAN]
- Diazoxide (JAN/USP/INN)
- 2H-1,2, 4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide
- 2H-1,2,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide
- 7-Chloro-3-methyl-1lambda~4~,2,4-benzothiadiazin-1-ol 1-oxide
- 7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
- 7-Cloro-3-metil-2H-1,2,4-benzotiodiazina-1,1-diossido
- 7-Cloro-3-metil-2H-1,2,4-benzotiodiazina-1,1-diossido [Italian]
- 7-chloro-3-methyl-4H-1
- O5CB12L4FN
Reported adverse events
- Chest pain
- Hypotension
- Pulmonary hypertension
- Tachycardia
- Diabetic ketoacidosis
- Hirsutism
- Neutropenia
- Thrombocytopenia
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