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DORZOLAMIDE

SynDRA canonical compound SYN0006485 — structure-anchored drug synonym record

All known targets

• CA2
• CA1
• CA12
• CA14
• CA4
• CA7
• AR
• CAN2
• mtcA1
• cynT
• ca1
• NCE103

Mechanisms of action (all sources)

• Carbonic anhydrase inhibitor
• CA2 INHIBITOR
• Carbonic anhydrase II inhibitor

Drug classes

• Carbonic Anhydrase Inhibitors
• Carbonic Anhydrase Inhibitor
• Antihypertensive Agents
• Cardiovascular Agents
• Enzyme Inhibitors

ATC classes

• S01E · ANTIGLAUCOMA PREPARATIONS AND MIOTICS

Cross-references

• PubChem CID: 5284549
• ChEMBL: CHEMBL218490
• DrugBank: DB00869
• ChEBI: CHEBI:4702
• KEGG: D00653
• RxNorm: 60207
• PDB: ETS
• Wikipedia: Dorzolamide
• TTD: D05UYW
• LINCS BRD: BRD-K48617017

Synonyms

• dorzolamide hydrochloride
• dorzolamide HCl
• Dorzolamida
• Dorzolamide, trans-(-)-
• Dorzant
• Trusopt
• Dorzolamide (DZA)
• Dorzolamide (INN)
• Trusopt (TN)
• (4S,6S)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
• (4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide
• (4S,6S)-4-Ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid amide
• (4S,trans)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
• (4S-TRANS)-4-(ETHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE
• 4S,6S-Dorzolamide
• 9JDX055TW1
• CHEBI:4702
• DORZOLAMIDE [INN]
• Dorzolamide impurity A
• 4-Ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid amide
• 4-ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda6-thieno[2,3-b]thiopyran-2-sulfonic acid amide
• Dorzolamide [INN:BAN]
• UNII 9JDX055TW1
• SR-05000001449
• 1cil
• 4H-Thieno(2,3-b)thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, (4S,6S)-
• 4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, (4S,6S)-
• DORZOLAMIDE [MI]
• Prestwick0_001116
• Prestwick1_001116
• Prestwick2_001116
• Prestwick3_001116
• DORZOLAMIDE [VANDF]
• SCHEMBL24061
• BSPBio_001252
• DORZOLAMIDE [WHO-DD]
• MLS006011430
• BIDD:GT0306

Reported adverse events

• Hypersensitivity
• Stevens-Johnson syndrome
• Alopecia
• Arrhythmia
• Arthralgia
• Asthenia
• Bronchospasm
• Gastrointestinal pain
• Pruritus
• Rales
• Vertigo
• Angioedema